WormBase Tree Display for Gene: WBGene00000549
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| WBGene00000549 | SMap | S_parent | Sequence | R107 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cls-2 | Person_evidence | WBPerson283 | |||||
| Sequence_name | R107.6 | ||||||||
| Molecular_name | R107.6a | ||||||||
| R107.6a.1 | |||||||||
| CE37546 | |||||||||
| R107.6b | |||||||||
| CE47893 | |||||||||
| R107.6b.1 | |||||||||
| Other_name | CELE_R107.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cls-2 | ||||||||
| DB_info | Database | AceView | gene | 3K147 | |||||
| WormQTL | gene | WBGene00000549 | |||||||
| WormFlux | gene | WBGene00000549 | |||||||
| NDB | locus_tag | CELE_R107.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000549|UniProtKB=P32744 | |||||||
| family | PTHR21567 | ||||||||
| NCBI | gene | 176280 | |||||||
| RefSeq | protein | NM_001276794.3 | |||||||
| NM_066604.6 | |||||||||
| SwissProt | UniProtAcc | P32744 | |||||||
| TrEMBL | UniProtAcc | K8ESK4 | |||||||
| UniProt_GCRP | UniProtAcc | P32744 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cls | ||||||||
| Allele (56) | |||||||||
| Strain | WBStrain00049947 | ||||||||
| WBStrain00049944 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (52) | |||||||||
| Contained_in_operon | CEOP3572 | ||||||||
| Ortholog (46) | |||||||||
| Paralog | WBGene00000491 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00015580 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00013847 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cls-2 encodes one of three predicted orthologs of mammalian CLASPs and of Drosophila ORBIT/MAST, microtubule-binding proteins required for fibroblast polarization and mitosis; cls-2 is required in mass RNAi assays for embryonic development and normal mitotic spindles; it has been claimed that, in an RNAi screen of potential microtubule tip-binding proteins, only cls-2(RNAi) yielded embryonic lethality and meiotic defects. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00006026 | |||||||||
| WBPaper00012870 | |||||||||
| WBPaper00013064 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable microtubule binding activity. Involved in cytoplasmic streaming; mitotic cytokinesis; and organelle organization. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Expressed in embryonic cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R107.6a | |||||||
| R107.6b | |||||||||
| Corresponding_CDS_history | R107.6:wp132 | ||||||||
| Corresponding_transcript | R107.6a.1 | ||||||||
| R107.6b.1 | |||||||||
| Other_sequence | CGC00220_1 | ||||||||
| Oden_isotig13949 | |||||||||
| FD514397.1 | |||||||||
| CJC00739_1 | |||||||||
| CSC00085_1 | |||||||||
| Oden_isotig13948 | |||||||||
| CBC03270_1 | |||||||||
| Associated_feature | WBsf645456 | ||||||||
| WBsf654984 | |||||||||
| WBsf659379 | |||||||||
| WBsf981540 | |||||||||
| WBsf225511 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr10026 | ||||||||
| Expr1017846 | |||||||||
| Expr1030330 | |||||||||
| Expr1155345 | |||||||||
| Expr2010253 | |||||||||
| Expr2028495 | |||||||||
| Drives_construct | WBCnstr00037460 | ||||||||
| Construct_product | WBCnstr00020442 | ||||||||
| WBCnstr00020444 | |||||||||
| WBCnstr00037460 | |||||||||
| Antibody | WBAntibody00000683 | ||||||||
| WBAntibody00002342 | |||||||||
| WBAntibody00002822 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (143) | |||||||||
| Interaction (97) | |||||||||
| Map_info | Map | III | Position | 0.122359 | Error | 0.003132 | |||
| Positive | Positive_clone | R107 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Sequence connection from [Oegema K, Hyman AA] [090402 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
