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WormBase Tree Display for Gene: WBGene00000549

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Name Class

WBGene00000549SMapS_parentSequenceR107
IdentityVersion1
NameCGC_namecls-2Person_evidenceWBPerson283
Sequence_nameR107.6
Molecular_nameR107.6a
R107.6a.1
CE37546
R107.6b
CE47893
R107.6b.1
Other_nameCELE_R107.6Accession_evidenceNDBBX284603
Public_namecls-2
DB_infoDatabaseAceViewgene3K147
WormQTLgeneWBGene00000549
WormFluxgeneWBGene00000549
NDBlocus_tagCELE_R107.6
PanthergeneCAEEL|WormBase=WBGene00000549|UniProtKB=P32744
familyPTHR21567
NCBIgene176280
RefSeqproteinNM_001276794.3
NM_066604.6
SwissProtUniProtAccP32744
TrEMBLUniProtAccK8ESK4
UniProt_GCRPUniProtAccP32744
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcls
Allele (56)
StrainWBStrain00049947
WBStrain00049944
RNASeq_FPKM (74)
GO_annotation00024138
00024139
00024140
00040999
00041000
00041001
00041002
00041003
00041004
00041005
00041006
00041007
00041008
00041009
00041010
00041011
00041012
00041013
00041014
00041015
00041016
00041017
00041018
00041019
00041020
00041021
00041022
00041023
00041024
00041025
00041026
00041027
00041028
00041029
00041030
00041031
00041032
00041033
00041034
00041035
00041036
00041037
00041038
00041039
00041040
00041041
00041042
00041043
00041044
00041045
00041046
00041047
Contained_in_operonCEOP3572
Ortholog (46)
ParalogWBGene00000491Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015580Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00013847Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptioncls-2 encodes one of three predicted orthologs of mammalian CLASPs and of Drosophila ORBIT/MAST, microtubule-binding proteins required for fibroblast polarization and mitosis; cls-2 is required in mass RNAi assays for embryonic development and normal mitotic spindles; it has been claimed that, in an RNAi screen of potential microtubule tip-binding proteins, only cls-2(RNAi) yielded embryonic lethality and meiotic defects.Paper_evidenceWBPaper00004403
WBPaper00005654
WBPaper00006026
WBPaper00012870
WBPaper00013064
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable microtubule binding activity. Involved in cytoplasmic streaming; mitotic cytokinesis; and organelle organization. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Expressed in embryonic cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR107.6a
R107.6b
Corresponding_CDS_historyR107.6:wp132
Corresponding_transcriptR107.6a.1
R107.6b.1
Other_sequenceCGC00220_1
Oden_isotig13949
FD514397.1
CJC00739_1
CSC00085_1
Oden_isotig13948
CBC03270_1
Associated_featureWBsf645456
WBsf654984
WBsf659379
WBsf981540
WBsf225511
Experimental_infoRNAi_result (12)
Expr_patternExpr10026
Expr1017846
Expr1030330
Expr1155345
Expr2010253
Expr2028495
Drives_constructWBCnstr00037460
Construct_productWBCnstr00020442
WBCnstr00020444
WBCnstr00037460
AntibodyWBAntibody00000683
WBAntibody00002342
WBAntibody00002822
Microarray_results (23)
Expression_cluster (143)
Interaction (97)
Map_infoMapIIIPosition0.122359Error0.003132
PositivePositive_cloneR107Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (35)
RemarkSequence connection from [Oegema K, Hyman AA] [090402 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene