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WormBase Tree Display for Gene: WBGene00012185

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Name Class

WBGene00012185SMapS_parentSequenceW01F3
IdentityVersion1
NameSequence_nameW01F3.2
Molecular_nameW01F3.2
W01F3.2.1
CE16530
Other_nameCELE_W01F3.2Accession_evidenceNDBBX284605
Public_nameW01F3.2
DB_infoDatabaseAceViewgene5V131
WormQTLgeneWBGene00012185
WormFluxgeneWBGene00012185
NDBlocus_tagCELE_W01F3.2
PanthergeneCAEEL|WormBase=WBGene00012185|UniProtKB=O62390
familyPTHR10201
NCBIgene180351
RefSeqproteinNM_075591.6
TREEFAMTREEFAM_IDTF344186
TrEMBLUniProtAccO62390
UniProt_GCRPUniProtAccO62390
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (53)
RNASeq_FPKM (74)
Ortholog (40)
ParalogWBGene00006987Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010423Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010524Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016283Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020646Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019212Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00012364Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00194737Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionEnriched in AIB; SIB; germline precursor cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; manganese chloride; and sodium arsenite based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Human MMP9 enables identical protein binding activity; metalloendopeptidase activity; and serine-type endopeptidase activity. Is predicted to encode a protein with the following domain: Hemopexin-like domain superfamily. Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (122)
Molecular_infoCorresponding_CDSW01F3.2
Corresponding_transcriptW01F3.2.1
Other_sequenceDviv_isotig31079
CBC02137_1
Acan_isotig12815
Tcir_isotig04024
Hbac_isotig02725
CR07048
CRC02265_1
Tcol_isotig02099
CR00258
Tcol_isotig02100
Associated_featureWBsf647751
WBsf1003606
WBsf1003607
WBsf1021987
WBsf233211
WBsf233212
Experimental_infoRNAi_resultWBRNAi00054529Inferred_automaticallyRNAi_primary
WBRNAi00036151Inferred_automaticallyRNAi_primary
Expr_patternExpr1012510
Expr1035387
Expr1158075
Expr2006671
Expr2024888
Drives_constructWBCnstr00030077
Construct_productWBCnstr00030077
Microarray_results (20)
Expression_cluster (287)
Interaction (201)
Map_infoPositivePositive_cloneW01F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV25.0306
MethodGene