WormBase Tree Display for Gene: WBGene00011737
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WBGene00011737 | SMap | S_parent | Sequence | T12G3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | sqst-1 | Paper_evidence | WBPaper00042170 | |||
Person_evidence | WBPerson716 | ||||||
Sequence_name | T12G3.1 | ||||||
Molecular_name | T12G3.1a | ||||||
T12G3.1a.1 | |||||||
CE37554 | |||||||
T12G3.1b | |||||||
CE45860 | |||||||
T12G3.1b.1 | |||||||
Other_name | CELE_T12G3.1 | Accession_evidence | NDB | BX284604 | |||
Public_name | sqst-1 | ||||||
DB_info | Database (11) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sqst | ||||||
Allele (53) | |||||||
Strain | WBStrain00001490 | ||||||
WBStrain00037114 | |||||||
WBStrain00037157 | |||||||
Component_of_genotype | WBGenotype00000083 | ||||||
WBGenotype00000084 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Ortholog (32) | |||||||
Paralog | WBGene00012067 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00012516 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00015552 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00021495 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | sqst-1 encodes a protein with similarity to mammalian sequestosome 1(SQSTM1)/p62, a signal transduction or adaptor protein involved in receptor-mediated signalling pathways; SQST-1 is weakly expressed in embryos and exhibits a diffuse, cytoplasmic localization; SQST-1 is selectively removed by autophagy during embryogenesis. | Paper_evidence | WBPaper00036384 | |||
WBPaper00041409 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 12 Oct 2012 00:00:00 | ||||||
Automated_description | Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Located in cytoplasm. Expressed in several structures, including head; hypodermal cell; muscle cell; tail; and vulva. Human ortholog(s) of this gene implicated in Paget's disease of bone 3; distal myopathy with rimmed vacuoles; and neurodegenerative disease (multiple). Is an ortholog of human SQSTM1 (sequestosome 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:332 | Homo sapiens | Paper_evidence | WBPaper00066343 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 31 Aug 2021 00:00:00 | ||||||
Potential_model (5) | |||||||
Models_disease_asserted | WBDOannot00001040 | ||||||
Molecular_info | Corresponding_CDS | T12G3.1a | |||||
T12G3.1b | |||||||
Corresponding_CDS_history | T12G3.1:wp132 | ||||||
Corresponding_transcript | T12G3.1a.1 | ||||||
T12G3.1b.1 | |||||||
Other_sequence | CBC08481_1 | ||||||
CR00634 | |||||||
CRC06360_1 | |||||||
CBC06086_1 | |||||||
CR03354 | |||||||
CBC12582_1 | |||||||
CR01694 | |||||||
CJC06184_1 | |||||||
CRC08734_1 | |||||||
CRC12404_1 | |||||||
Associated_feature | WBsf646442 | ||||||
WBsf660776 | |||||||
WBsf660777 | |||||||
WBsf660778 | |||||||
WBsf981832 | |||||||
WBsf998015 | |||||||
WBsf1018314 | |||||||
WBsf229233 | |||||||
WBsf229234 | |||||||
WBsf229235 | |||||||
Experimental_info | RNAi_result | WBRNAi00113609 | Inferred_automatically | RNAi_primary | |||
WBRNAi00114688 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00033299 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00018644 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00053225 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (19) | |||||||
Drives_construct | WBCnstr00002349 | ||||||
WBCnstr00004318 | |||||||
WBCnstr00006906 | |||||||
WBCnstr00014783 | |||||||
WBCnstr00030429 | |||||||
Construct_product | WBCnstr00006906 | ||||||
WBCnstr00019922 | |||||||
WBCnstr00030429 | |||||||
Antibody | WBAntibody00002145 | ||||||
WBAntibody00002774 | |||||||
WBAntibody00002865 | |||||||
WBAntibody00002887 | |||||||
Microarray_results (23) | |||||||
Expression_cluster (335) | |||||||
Interaction (77) | |||||||
Map_info | Map | IV | Position | 5.51952 | |||
Positive | Positive_clone | T12G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (36) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |