WormBase Tree Display for Gene: WBGene00011676

WBGene00011676 SMap: S_parent: Sequence: T10B9
  Identity: Version: 2
    Name: CGC_name: cyp-13A2
      Sequence_name: T10B9.7
      Molecular_name: T10B9.7
        T10B9.7.1
        CE01659
      Other_name: CELE_T10B9.7 Accession_evidence: NDB BX284602
      Public_name: cyp-13A2
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-13A2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (68)
    RNASeq_FPKM (74)
    GO_annotation: 00079959
      00079960
      00079961
      00118915
      00118916
      00118917
      00118918
    Contained_in_operon: CEOP2766
    Ortholog: WBGene00067224 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024326 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            WormBase-Compara
      WBGene00130660 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00193620 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00092752 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00104757 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00119176 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00095336 Pristionchus pacificus From_analysis: Inparanoid_8
      CSP26.g7741 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g13575 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9007 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP32.g9796 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP39.g173 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g21780 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g2330 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cnig_chr_II.g4010 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold560.g3897 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01510.g21371 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04743 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_004785 Caenorhabditis remanei From_analysis: WormBase-Compara
      Pan_g12829 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g13866 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g17621 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g17830 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g17831 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g20387 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g2061 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20181100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5591 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00095463 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00095508 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00096190 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00100474 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00102738 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00104661 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00105897 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00106365 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00106421 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00107154 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00273159 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00273166 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275927 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00280647 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00281646 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00282015 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00287393 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0033304 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0033978 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0033979 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0033980 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0033982 Drosophila melanogaster From_analysis: OMA
            OrthoFinder
            SonicParanoid
      FB:FBgn0038194 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0015714 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      FB:FBgn0031726 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            SonicParanoid
      ZFIN:ZDB-GENE-041114-102 Danio rerio From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-050604-1 Danio rerio From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-060929-96 Danio rerio From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-030131-8805 Danio rerio From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:2640 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:2637 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:2638 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:11609 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:17450 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      HGNC:51504 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:88609 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:88610 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:106099 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:98497 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:1858451 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:1930638 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:2449818 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:3646373 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:3714859 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      MGI:3769707 Mus musculus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:3826 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:628626 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:1595919 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:708392 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:628709 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      RGD:708379 Rattus norvegicus From_analysis: Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
    Paralog (12)
    Structured_description: Concise_description: cyp-13A2 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates. Curator_confirmed: WBPerson1843
          Date_last_updated: 20 Nov 2008 00:00:00
      Automated_description: Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:8552 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2638)
      DOID:3526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11609)
      DOID:2987 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2637)
      DOID:9952 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2638)
      DOID:0112251 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11609)
      DOID:0080630 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2638)
      DOID:10825 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2638)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2637)
  Molecular_info: Corresponding_CDS: T10B9.7
    Corresponding_transcript: T10B9.7.1
    Other_sequence (11)
    Associated_feature: WBsf650458
      WBsf650459
      WBsf989147
      WBsf989148
      WBsf1012903
      WBsf1012904
  Experimental_info: RNAi_result: WBRNAi00035425 Inferred_automatically: RNAi_primary
      WBRNAi00092621 Inferred_automatically: RNAi_primary
      WBRNAi00018528 Inferred_automatically: RNAi_primary
      WBRNAi00053020 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025189
      Expr1156620
      Expr2010682
      Expr2028922
    Drives_construct: WBCnstr00030477
    Construct_product: WBCnstr00030477
    Microarray_results (20)
    Expression_cluster (232)
    Interaction (28)
  Map_info: Map: II Position: 1.71406 Error: 0.000287
    Positive: Positive_clone: T10B9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026952
    WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00064598
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene