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WormBase Tree Display for Gene: HGNC:17450

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Name Class

HGNC:17450IdentityNameCGC_nameCYP3A43Inferred_automaticallyAGR_import
Other_nameRGD:1350489
MGC119315
MGC119316
cytochrome P450 3A43
cytochrome P450 polypeptide 43
cytochrome P450, family 3, subfamily A, polypeptide 43
cytochrome P450, subfamily IIIA, polypeptide 43
Public_nameCYP3A43
DB_infoDatabaseHGNCid17450
AGRcURIHGNC:17450
EnsEMBLENSEMBL_geneIDENSG00000021461
UniProtUniProt_ACQ9HB55
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
Ortholog (13)
Structured_descriptionAutomated_descriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]Inferred_automaticallyAGR_import