WormBase Tree Display for Gene: RGD:708379
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| RGD:708379 | Identity | Name | CGC_name | Cyp3a2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Cyp3a2 | |||||
| DB_info | Database | RGD | id | 708379 | ||
| AGR | cURI | RGD:708379 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000032560 | ||||
| ENSRNOG00000062027 | ||||||
| UniProt | UniProt_AC | P05183 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog (13) | ||||||
| Structured_description | Automated_description | Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in oxidative demethylation and xenobiotic metabolic process. Predicted to be located in cytoplasm. Used to study anxiety disorder. Biomarker of cholestasis and end stage renal disease. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5); PARTICIPATES IN tamoxifen pharmacokinetics pathway; artemether pharmacokinetics pathway; axitinib pharmacokinetics pathway; INTERACTS WITH (R,R,R)-alpha-tocopherol; (S)-nicotine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane. | Inferred_automatically | AGR_import |
