Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00010988

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00010988SMapS_parentSequenceR03D7
IdentityVersion2
NameCGC_namemetr-1Person_evidenceWBPerson1711
Sequence_nameR03D7.1
Molecular_nameR03D7.1
R03D7.1.1
CE01609
Other_nameCELE_R03D7.1Accession_evidenceNDBBX284602
Public_namemetr-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
220 Apr 2011 10:05:24WBPerson2970Name_changeCGC_namemetr-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmetr
AlleleWBVar01499702
WBVar01499347
WBVar01499348
WBVar00091808
WBVar00238564
WBVar01498435
WBVar00765643
WBVar00765644
WBVar00765645
WBVar00765646
WBVar00765647
WBVar00765648
WBVar00765649
WBVar00765650
WBVar00765651
WBVar00052327
WBVar00765652
WBVar00765653
WBVar01379267
WBVar01784494
WBVar00765654
WBVar01379278
WBVar00765655
WBVar00765656
WBVar00765657
WBVar00765658
WBVar00765659
WBVar00765660
WBVar00765661
WBVar01546889
WBVar00765662
WBVar00765663
WBVar00175522
WBVar00765664
WBVar00765665
WBVar00175523
WBVar00765666
WBVar00765667
WBVar01244379
WBVar00377247
WBVar00377248
WBVar00377249
WBVar00377250
WBVar00377251
WBVar00377252
WBVar00377253
WBVar00377254
WBVar00377255
WBVar00377256
WBVar02145345
WBVar01439727
WBVar01488614
WBVar01498940
WBVar01477971
WBVar00105562
StrainWBStrain00001842
WBStrain00002165
WBStrain00031469
RNASeq_FPKM (74)
GO_annotation (23)
Ortholog (39)
ParalogWBGene00015512Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00020491Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionmetr-1 encodes a protein orthologous to the human gene Methionine synthase (MTR), which is involved in the conversion of homocysteine to form methionine.Paper_evidenceWBPaper00042203
Curator_confirmedWBPerson324
WBPerson1823
WBPerson567
Date_last_updated07 May 2013 00:00:00
Automated_descriptionPredicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9352Homo sapiensPaper_evidenceWBPaper00042203
Curator_confirmedWBPerson324
Date_last_updated13 Mar 2023 00:00:00
Potential_model (14)
Models_disease_assertedWBDOannot00000175
Molecular_infoCorresponding_CDSR03D7.1
Corresponding_transcriptR03D7.1.1
Other_sequence (51)
Associated_featureWBsf222084
WBsf222085
Experimental_infoRNAi_resultWBRNAi00071221Inferred_automaticallyRNAi_primary
WBRNAi00034551Inferred_automaticallyRNAi_primary
WBRNAi00090587Inferred_automaticallyRNAi_primary
WBRNAi00051170Inferred_automaticallyRNAi_primary
WBRNAi00106971Inferred_automaticallyRNAi_primary
WBRNAi00017346Inferred_automaticallyRNAi_primary
Expr_patternChronogram417
Chronogram1093
Expr6447
Expr6448
Expr1028258
Expr1034818
Expr1154877
Expr2013538
Expr2031772
Drives_constructWBCnstr00002636
WBCnstr00004383
Regulate_expr_clusterWBPaper00060951:metr-1(os521)_downregulated
WBPaper00060951:metr-1(os521)_upregulated
Microarray_results (20)
Expression_cluster (213)
Interaction (110)
Map_infoMapIIPosition3.13342Error0.000132
PositivePositive_cloneR03D7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (25)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene