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WormBase Tree Display for Gene: WBGene00010788

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Name Class

WBGene00010788SMapS_parentSequenceK12G11
IdentityVersion2
NameCGC_namesulp-4Person_evidenceWBPerson2233
Sequence_nameK12G11.1
Molecular_nameK12G11.1
K12G11.1.1
CE12208
Other_nameCELE_K12G11.1Accession_evidenceNDBBX284605
Public_namesulp-4
DB_infoDatabaseAceViewgene5M359
WormQTLgeneWBGene00010788
WormFluxgeneWBGene00010788
NDBlocus_tagCELE_K12G11.1
PanthergeneCAEEL|WormBase=WBGene00010788|UniProtKB=G5EEA7
familyPTHR11814
NCBIgene179626
RefSeqproteinNM_073588.5
TrEMBLUniProtAccG5EEA7
UniProt_GCRPUniProtAccG5EEA7
OMIMgene604943
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
219 Jan 2005 16:30:54WBPerson2970Name_changeCGC_namesulp-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsulp
Allele (46)
StrainWBStrain00032322
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (58)
ParalogWBGene00013963Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00012259Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016945Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017464Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018283Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020914Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010789Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionsulp-4 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-4 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-4 exhibits robust transport of sulfate and more modest transport of chloride ions and oxalate; a SULP-4::GFP fusion is expressed in the apical canaliculae of the excretory cell and also in some head neurons.Paper_evidenceWBPaper00025075
Curator_confirmedWBPerson1843
Date_last_updated13 Sep 2006 00:00:00
Automated_descriptionEnables chloride transmembrane transporter activity; oxalate transmembrane transporter activity; and sulfate transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in apical plasma membrane. Expressed in excretory cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61. Is an ortholog of human SLC26A5 (solute carrier family 26 member 5) and SLC26A6 (solute carrier family 26 member 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110513Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9359)
Molecular_infoCorresponding_CDSK12G11.1
Corresponding_transcriptK12G11.1.1
Other_sequenceSC01391
JI175411.1
Dviv_isotig27911
MJ04121
FK802149.1
GR978214.1
MJC03467_1
JI181216.1
Associated_featureWBsf718413
WBsf1001463
WBsf232561
WBsf232562
WBsf232563
Experimental_infoRNAi_resultWBRNAi00017060Inferred_automaticallyRNAi_primary
WBRNAi00034316Inferred_automaticallyRNAi_primary
WBRNAi00050673Inferred_automaticallyRNAi_primary
Expr_patternExpr3249
Expr3256
Expr1020848
Expr1154382
Expr2017115
Expr2035251
Drives_constructWBCnstr00011252
WBCnstr00011259
WBCnstr00031144
WBCnstr00042690
Construct_productWBCnstr00011259
WBCnstr00031144
Microarray_results (19)
Expression_cluster (112)
Interaction (13)
Map_infoMapVPosition3.48341Error0.007824
PositivePositive_cloneK12G11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00025075
WBPaper00035475
WBPaper00035539
WBPaper00038491
WBPaper00054370
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene