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WormBase Tree Display for Gene: WBGene00010778

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Name Class

WBGene00010778SMapS_parentSequenceK11H3
IdentityVersion2
NameCGC_namegpdh-2Person_evidenceWBPerson1851
Sequence_nameK11H3.1
Molecular_name (12)
Other_nameCELE_K11H3.1Accession_evidenceNDBBX284603
Public_namegpdh-2
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
212 Sep 2006 10:49:55WBPerson2970Name_changeCGC_namegpdh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpdh
Allele (77)
StrainWBStrain00003775
WBStrain00032179
WBStrain00048030
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP3795
Ortholog (48)
ParalogWBGene00009824Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpdh-2 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-2 activity via large-scale RNAi screens results in no obvious defects, expression of a gpdh-2 cDNA in Saccharomyces cerevisiae hog1 mutants is able to rescue the high osmolarity-sensitive growth phenotype of these mutants, suggesting that gpdh-2 encodes a functional glycerol 3-phosphate dehydrogenase.Paper_evidenceWBPaper00003607
Curator_confirmedWBPerson1843
Date_last_updated11 Dec 2006 00:00:00
Automated_descriptionPredicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28956)
Molecular_infoCorresponding_CDSK11H3.1a
K11H3.1b
K11H3.1c
K11H3.1d
Corresponding_CDS_historyK11H3.1:wp85
Corresponding_transcriptK11H3.1a.1
K11H3.1b.1
K11H3.1c.1
K11H3.1d.1
Other_sequence (179)
Associated_feature (14)
Experimental_infoRNAi_resultWBRNAi00034302Inferred_automaticallyRNAi_primary
WBRNAi00092280Inferred_automaticallyRNAi_primary
WBRNAi00050633Inferred_automaticallyRNAi_primary
WBRNAi00017038Inferred_automaticallyRNAi_primary
WBRNAi00092279Inferred_automaticallyRNAi_primary
WBRNAi00006047Inferred_automaticallyRNAi_primary
Expr_patternExpr3987
Expr6392
Expr1018067
Expr1034717
Expr1154341
Expr2012210
Expr2030446
Drives_constructWBCnstr00004195
WBCnstr00011798
WBCnstr00031154
Construct_productWBCnstr00031154
Microarray_results (34)
Expression_clusterWBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00035073:mitochondria_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:excretory-cell_larva_enriched
WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038289:oocyte_protein
WBPaper00040221:DAF-12_target_ALF4
WBPaper00041072:UTX-1_interacting_protein
WBPaper00043951:insoluble_protein_day16_N2
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044746:aging_upregulated_HeatShock
WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
WBPaper00045314:S.aureus-induced_N2
WBPaper00045316:prg-1_downregulated_L3
WBPaper00045521:Gender_Neutral
WBPaper00045729:gld-2(RNAi)_upregulated
WBPaper00045934:wrn-1(gk99)_downregulated
WBPaper00046303:P.aeruginosa_downregulated_protein
WBPaper00048910:mRNA-interacting_protein
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049018:swsn-2.2(RNAi)_downregulated
WBPaper00049325:CB4856_vs_N2_DEG
WBPaper00050080:rbr-2(tm3141)_upregulated
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050698:DEP-1_interacting
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051555:atm-1(gk186)_regulated_protein
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053615:SMO-1_target
WBPaper00053771:up_at_3h-NaCl
WBPaper00055049:S.gordonii_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055648:germline_expressed
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056501:P.aeruginosa_upregulated_mitochondria-protein
WBPaper00057288:Cold_downregulated_protein
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058725:sftb-1(cer39)_downregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059254:CSR-1_interacting
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
WBPaper00059471:EGL-43_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
WBPaper00059816:crh-1(n3315)_downrgulated
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060886:spr-5(by101)_upregulated
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:hyp7_C_lineage
WBPaper00061377:MYRF-1_interacting
WBPaper00061527:R07E4.5-skp-1_1608
WBPaper00061527:tars-1-AFFX-r2-3026-5_at
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062554:MAGU-2_interacting
WBPaper00062590:Aging_upregulated_coelomocyte
WBPaper00062669:extracellular-vesicle_protein
WBPaper00063976:micu-1(bon20)_downregulated
WBPaper00064071:NHR-49_interacting
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064494:postdauer_downregulated_AWA
WBPaper00064992:Eugenol_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065158:AFD_depleted
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00005124:estrogen_10-5M_regulated
WBPaper00025032:PAL-1_target_genes
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030985:Erwinia_carotovora_upregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00035560:ahr-1_upregulated
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osmotically_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00037695:WC_5-day
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00040210:Chlorpyrifos_24C_regulated
WBPaper00040426:CYD-1_CDK-4_downregulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_developing
WBPaper00040858:eQTL_regulated_juvenile
WBPaper00040858:eQTL_regulated_old
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00045263:isp-1(qm150)_downregulated
WBPaper00045960:L4-lethargus_upregulated
[cgc5767]:cluster_15
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(101_min)
[cgc5767]:expression_class_E_pi(122_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MDE
[cgc5767]:expression_class_MD_pd(53_min)
[cgc5767]:expression_class_ME
Interaction (111)
Map_infoMapIIIPosition1.12662Error0.001222
PositivePositive_cloneK11H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene