WormBase Tree Display for Gene: WBGene00009824
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| WBGene00009824 | SMap | S_parent | Sequence | F47G4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gpdh-1 | Person_evidence | WBPerson1851 | |||||
| Sequence_name | F47G4.3 | ||||||||
| Molecular_name | F47G4.3 | ||||||||
| F47G4.3.1 | |||||||||
| CE18701 | |||||||||
| Other_name | CELE_F47G4.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | gpdh-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 12 Sep 2006 10:48:07 | WBPerson2970 | Name_change | CGC_name | gpdh-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpdh | ||||||||
| Allele (40) | |||||||||
| Strain | WBStrain00032072 | ||||||||
| WBStrain00048030 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (49) | |||||||||
| Paralog | WBGene00010778 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans via glycerol biosynthesis; regulation of gpdh-1 expression is controlled, in part, by a pathway that includes the OSM-8 mucin and the PTR-23 Patched-like receptor. | Paper_evidence | WBPaper00006432 | |||||
| WBPaper00038064 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in NADH oxidation and glycerol-3-phosphate metabolic process. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110219 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:28956) | ||||
| Molecular_info | Corresponding_CDS | F47G4.3 | |||||||
| Corresponding_transcript | F47G4.3.1 | ||||||||
| Other_sequence | GO238924.1 | ||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00032450 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00003699 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047681 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3986 | ||||||||
| Expr1010915 | |||||||||
| Expr1034292 | |||||||||
| Expr1151522 | |||||||||
| Expr2012209 | |||||||||
| Expr2030445 | |||||||||
| Drives_construct | WBCnstr00000751 | ||||||||
| WBCnstr00008693 | |||||||||
| WBCnstr00031890 | |||||||||
| WBCnstr00038242 | |||||||||
| Construct_product | WBCnstr00031890 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (287) | |||||||||
| Interaction (173) | |||||||||
| Map_info | Map | I | Position | 23.0163 | Error | 0.010903 | |||
| Positive | Positive_clone | F47G4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (32) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
