WormBase Tree Display for Gene: WBGene00010778
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| WBGene00010778 | SMap | S_parent | Sequence | K11H3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gpdh-2 | Person_evidence | WBPerson1851 | |||||
| Sequence_name | K11H3.1 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_K11H3.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | gpdh-2 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 12 Sep 2006 10:49:55 | WBPerson2970 | Name_change | CGC_name | gpdh-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpdh | ||||||||
| Allele (77) | |||||||||
| Strain | WBStrain00003775 | ||||||||
| WBStrain00032179 | |||||||||
| WBStrain00048030 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Contained_in_operon | CEOP3795 | ||||||||
| Ortholog (48) | |||||||||
| Paralog | WBGene00009824 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpdh-2 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-2 activity via large-scale RNAi screens results in no obvious defects, expression of a gpdh-2 cDNA in Saccharomyces cerevisiae hog1 mutants is able to rescue the high osmolarity-sensitive growth phenotype of these mutants, suggesting that gpdh-2 encodes a functional glycerol 3-phosphate dehydrogenase. | Paper_evidence | WBPaper00003607 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Dec 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110219 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:28956) | ||||
| Molecular_info | Corresponding_CDS | K11H3.1a | |||||||
| K11H3.1b | |||||||||
| K11H3.1c | |||||||||
| K11H3.1d | |||||||||
| Corresponding_CDS_history | K11H3.1:wp85 | ||||||||
| Corresponding_transcript | K11H3.1a.1 | ||||||||
| K11H3.1b.1 | |||||||||
| K11H3.1c.1 | |||||||||
| K11H3.1d.1 | |||||||||
| Other_sequence (179) | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00034302 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00092280 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050633 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017038 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092279 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006047 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3987 | ||||||||
| Expr6392 | |||||||||
| Expr1018067 | |||||||||
| Expr1034717 | |||||||||
| Expr1154341 | |||||||||
| Expr2012210 | |||||||||
| Expr2030446 | |||||||||
| Drives_construct | WBCnstr00004195 | ||||||||
| WBCnstr00011798 | |||||||||
| WBCnstr00031154 | |||||||||
| Construct_product | WBCnstr00031154 | ||||||||
| Microarray_results (34) | |||||||||
| Expression_cluster (151) | |||||||||
| Interaction (111) | |||||||||
| Map_info | Map | III | Position | 1.12662 | Error | 0.001222 | |||
| Positive | Positive_clone | K11H3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (17) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
