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WormBase Tree Display for Gene: WBGene00010778

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Name Class

WBGene00010778SMapS_parentSequenceK11H3
IdentityVersion2
NameCGC_namegpdh-2Person_evidenceWBPerson1851
Sequence_nameK11H3.1
Molecular_name (12)
Other_nameCELE_K11H3.1Accession_evidenceNDBBX284603
Public_namegpdh-2
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
212 Sep 2006 10:49:55WBPerson2970Name_changeCGC_namegpdh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpdh
Allele (77)
StrainWBStrain00003775
WBStrain00032179
WBStrain00048030
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP3795
Ortholog (48)
ParalogWBGene00009824Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpdh-2 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-2 activity via large-scale RNAi screens results in no obvious defects, expression of a gpdh-2 cDNA in Saccharomyces cerevisiae hog1 mutants is able to rescue the high osmolarity-sensitive growth phenotype of these mutants, suggesting that gpdh-2 encodes a functional glycerol 3-phosphate dehydrogenase.Paper_evidenceWBPaper00003607
Curator_confirmedWBPerson1843
Date_last_updated11 Dec 2006 00:00:00
Automated_descriptionPredicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28956)
Molecular_infoCorresponding_CDSK11H3.1a
K11H3.1b
K11H3.1c
K11H3.1d
Corresponding_CDS_historyK11H3.1:wp85
Corresponding_transcriptK11H3.1a.1
K11H3.1b.1
K11H3.1c.1
K11H3.1d.1
Other_sequenceMIC05690_1
FG583129.1
FK806244.1
TV00145
Tcol_isotig05517
RS10010
AYC03638_1
BU087933.1
FC544024.1
Oden_isotig05101
EX557361.1
FC546041.1
ACC18422_1
FK808678.1
FF679816.1
RS10310
FC550121.1
MC04651
EX009578.1
FF679626.1
FK807955.1
AE02469
FK803885.1
EY469729.1
RSC03254_1
MCC00282_1
ACC00574_1
HBC20271_1
BXC01368_1
GO239026.1
Name_isotig02417
GO238890.1
Oden_isotig05111
EX559984.1
Tcol_isotig05519
CSC01799_1
AYC02482_1
CBC04363_1
FE913163.1
GO238902.1
RSC04575_1
EX007054.1
EY465713.1
ACC06834_1
Oden_isotig05104
GO238964.1
FF681946.1
HG02431
GO239002.1
EX537354.1
Oden_isotig05108
ASC38078_1
Tcir_isotig10062
GO238878.1
EX562357.1
EY473349.1
JI168777.1
FK804507.1
GO238970.1
EW743113.1
EX547536.1
EY462092.1
HBC03506_1
EY462832.1
CRC05037_1
NAC00419_1
GO239030.1
GO238997.1
EX565384.1
FC543226.1
EY468189.1
FK805030.1
FC547880.1
Oden_isotig05109
EX565201.1
EX563150.1
Tcol_isotig05518
Oden_isotig05110
GO238914.1
EX563033.1
FC554626.1
Oden_isotig05100
AE03722
Tcol_isotig05520
BXC00038_1
GO238892.1
GO238917.1
ES744009.1
CSC01332_1
ACC19012_1
FC544392.1
EX015073.1
GO251483.1
PVC01609_1
PPC05272_1
MC00107
ACC27730_1
ES672851.1
OOC01707_1
FC553460.1
ACC26554_1
EY463085.1
EX565340.1
FK806950.1
FD516766.1
EX560747.1
GO238905.1
CV200936.1
GRC05459_1
Oden_isotig05103
JI171360.1
GR11238
FF681648.1
FC545627.1
BU087647.1
EX556342.1
FK809514.1
BUC00939_1
FK808055.1
GO252366.1
ACC12855_1
EX555685.1
ACC15473_1
BU666257.1
ACC16122_1
AE04194
FC546271.1
GO238975.1
Acan_isotig03556
Oden_isotig05105
EY466041.1
EW743873.1
BU665939.1
GO238915.1
FC555247.1
CR02308
TVC00835_1
EX914852.1
EY463769.1
FF681834.1
FK804456.1
SC00357
GO239004.1
FD517020.1
FF679520.1
EY462579.1
ES672860.1
EX565118.1
HGC05995_1
MI05971
Oden_isotig05102
PPC07545_1
EW743272.1
PPC17466_1
BXC01358_1
MI02091
Oden_isotig05107
JI172093.1
GO238950.1
GO238904.1
GO238980.1
CJC13854_1
DN153032.1
Acan_isotig11738
BXC00857_1
JO471647.1
GO238985.1
GO238895.1
Hbac_isotig01619
Dviv_isotig23680
Oden_isotig05106
FC552297.1
FF679326.1
Acan_isotig03555
GR978767.1
EY469224.1
GO238953.1
EY467748.1
BU088359.1
Associated_feature (14)
Experimental_infoRNAi_resultWBRNAi00034302Inferred_automaticallyRNAi_primary
WBRNAi00092280Inferred_automaticallyRNAi_primary
WBRNAi00050633Inferred_automaticallyRNAi_primary
WBRNAi00017038Inferred_automaticallyRNAi_primary
WBRNAi00092279Inferred_automaticallyRNAi_primary
WBRNAi00006047Inferred_automaticallyRNAi_primary
Expr_patternExpr3987
Expr6392
Expr1018067
Expr1034717
Expr1154341
Expr2012210
Expr2030446
Drives_constructWBCnstr00004195
WBCnstr00011798
WBCnstr00031154
Construct_productWBCnstr00031154
Microarray_results (34)
Expression_cluster (151)
Interaction (111)
Map_infoMapIIIPosition1.12662Error0.001222
PositivePositive_cloneK11H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene