WormBase Tree Display for Gene: WBGene00010403

WBGene00010403 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: otpl-8
      Sequence_name: H19J13.1
      Molecular_name: H19J13.1
        H19J13.1.1
        CE51331
      Other_name: CELE_H19J13.1 Accession_evidence: NDB BX284606
      Public_name: otpl-8
    DB_info: Database: AceView gene XM884
        WormQTL gene WBGene00010403
        WormFlux gene WBGene00010403
        NDB locus_tag CELE_H19J13.1
        Panther gene CAEEL|WormBase=WBGene00010403|UniProtKB=G5EDX5
          family PTHR21522
        NCBI gene 186752
        RefSeq protein NM_077644.6
        TREEFAM TREEFAM_ID TF313428
        TrEMBL UniProtAcc G5EDX5
        UniProt_GCRP UniProtAcc G5EDX5
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 07 Apr 2008 11:28:34 WBPerson2970 Name_change: CGC_name: otpl-8
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: otpl
    Allele (65)
    Strain: WBStrain00050999
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (45)
    Paralog: WBGene00017034 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00018478 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00018479 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00018480 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00015035 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017449 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00018477 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: otpl-8 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-8 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-8's paralogs include OTPL-1 through OTPL-7; OTPL-8 has no function in mass RNAi assays. Paper_evidence: WBPaper00031620
            WBPaper00031621
            WBPaper00031622
            WBPaper00031623
          Curator_confirmed: WBPerson567
          Date_last_updated: 04 Apr 2008 00:00:00
      Automated_description: Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: H19J13.1
    Corresponding_CDS_history: H19J13.1:wp252
    Corresponding_transcript: H19J13.1.1
    Other_sequence: BM01130
    Associated_feature: WBsf1007263
      WBsf1007264
      WBsf238053
  Experimental_info: RNAi_result: WBRNAi00033722 Inferred_automatically: RNAi_primary
      WBRNAi00016278 Inferred_automatically: RNAi_primary
      WBRNAi00049429 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025873
      Expr1153157
      Expr2014664
      Expr2032897
    Drives_construct: WBCnstr00031440
    Construct_product: WBCnstr00031440
    Microarray_results (16)
    Expression_cluster (90)
    Interaction: WBInteraction000153287
      WBInteraction000413423
  Map_info: Map: X Position: 7.0159
    Positive: Positive_clone: H19J13 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031620
    WBPaper00031622
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene