WormBase Tree Display for Gene: WBGene00010403
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WBGene00010403 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | otpl-8 | |||||
Sequence_name | H19J13.1 | ||||||
Molecular_name | H19J13.1 | ||||||
H19J13.1.1 | |||||||
CE51331 | |||||||
Other_name | CELE_H19J13.1 | Accession_evidence | NDB | BX284606 | |||
Public_name | otpl-8 | ||||||
DB_info | Database | AceView | gene | XM884 | |||
WormQTL | gene | WBGene00010403 | |||||
WormFlux | gene | WBGene00010403 | |||||
NDB | locus_tag | CELE_H19J13.1 | |||||
Panther | gene | CAEEL|WormBase=WBGene00010403|UniProtKB=G5EDX5 | |||||
family | PTHR21522 | ||||||
NCBI | gene | 186752 | |||||
RefSeq | protein | NM_077644.6 | |||||
TREEFAM | TREEFAM_ID | TF313428 | |||||
TrEMBL | UniProtAcc | G5EDX5 | |||||
UniProt_GCRP | UniProtAcc | G5EDX5 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | otpl | ||||||
Allele (65) | |||||||
Strain | WBStrain00050999 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Ortholog (45) | |||||||
Paralog | WBGene00017034 | Caenorhabditis elegans | From_analysis | TreeFam | |||
WormBase-Compara | |||||||
WBGene00018478 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00018479 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00018480 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00015035 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00017449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00018477 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | otpl-8 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-8 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-8's paralogs include OTPL-1 through OTPL-7; OTPL-8 has no function in mass RNAi assays. | Paper_evidence | WBPaper00031620 | |||
WBPaper00031621 | |||||||
WBPaper00031622 | |||||||
WBPaper00031623 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 04 Apr 2008 00:00:00 | ||||||
Automated_description | Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | H19J13.1 | |||||
Corresponding_CDS_history | H19J13.1:wp252 | ||||||
Corresponding_transcript | H19J13.1.1 | ||||||
Other_sequence | BM01130 | ||||||
Associated_feature | WBsf1007263 | ||||||
WBsf1007264 | |||||||
WBsf238053 | |||||||
Experimental_info | RNAi_result | WBRNAi00033722 | Inferred_automatically | RNAi_primary | |||
WBRNAi00016278 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00049429 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1025873 | ||||||
Expr1153157 | |||||||
Expr2014664 | |||||||
Expr2032897 | |||||||
Drives_construct | WBCnstr00031440 | ||||||
Construct_product | WBCnstr00031440 | ||||||
Microarray_results (16) | |||||||
Expression_cluster (90) | |||||||
Interaction | WBInteraction000153287 | ||||||
WBInteraction000413423 | |||||||
Map_info | Map | X | Position | 7.0159 | |||
Positive | Positive_clone | H19J13 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00031620 | ||||||
WBPaper00031622 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |