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WormBase Tree Display for Gene: WBGene00015035

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Name Class

WBGene00015035SMapS_parentSequenceB0212
IdentityVersion3
NameCGC_nameotpl-1
Sequence_nameB0212.1
Molecular_nameB0212.1a
B0212.1a.1
CE44425
B0212.1b
CE49039
B0212.1c
CE48561
B0212.1b.1
B0212.1c.1
Other_nameCELE_B0212.1Accession_evidenceNDBBX284604
Public_nameotpl-1
DB_infoDatabaseAceViewgene4E341
WormQTLgeneWBGene00015035
WormFluxgeneWBGene00015035
NDBlocus_tagCELE_B0212.1
PanthergeneCAEEL|WormBase=WBGene00015035|UniProtKB=U4PEQ1
familyPTHR21522
NCBIgene181841
RefSeqproteinNM_001392283.1
NM_001307511.1
NM_067973.4
TrEMBLUniProtAccU4PBH5
U4PEQ1
O45067
UniProt_GCRPUniProtAccU4PEQ1
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
207 Apr 2008 11:28:34WBPerson2970Name_changeCGC_nameotpl-1
327 Sep 2013 10:35:05WBPerson4025EventAcquires_mergeWBGene00044111
Acquires_mergeWBGene00044111
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classotpl
Allele (180)
StrainWBStrain00050964
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (40)
ParalogWBGene00010403Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017034Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00018478Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018479Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018480Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017449Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018477Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionotpl-1 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-1 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-1's paralogs include OTPL-2 through OTPL-8.Paper_evidenceWBPaper00031620
WBPaper00031621
WBPaper00031622
WBPaper00031623
Curator_confirmedWBPerson567
Date_last_updated04 Apr 2008 00:00:00
Automated_descriptionPredicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSB0212.1a
B0212.1b
B0212.1c
Corresponding_CDS_historyB0212.1:wp210
Corresponding_transcriptB0212.1a.1
B0212.1b.1
B0212.1c.1
Other_sequenceHGC05023_1
Tcol_isotig13542
GPC01423_1
Tcir_isotig14099
GP02880
Acan_isotig15944
HG09223
Associated_featureWBsf645877
WBsf659784
WBsf995984
WBsf995985
WBsf995986
WBsf1017084
Experimental_infoRNAi_resultWBRNAi00009576Inferred_automaticallyRNAi_primary
WBRNAi00038723Inferred_automaticallyRNAi_primary
Expr_patternExpr1010869
Expr1017170
Expr1142933
Expr1142938
Expr2014657
Expr2032890
Microarray_results (34)
Expression_cluster (123)
Interaction (13)
Map_infoMapIVPosition-3.14057Error0.003476
PositivePositive_cloneB0212Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031620
WBPaper00031622
WBPaper00038491
WBPaper00055090
WBPaper00056048
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene