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WormBase Tree Display for Gene: WBGene00009460

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Name Class

WBGene00009460SMapS_parentSequenceCHROMOSOME_I
IdentityVersion3
NameCGC_nameubr-5Person_evidenceWBPerson2634
WBPerson2601
Sequence_nameF36A2.13
Molecular_nameF36A2.13
F36A2.13.1
CE24948
F36A2.13.2
Other_namesog-1Paper_evidenceWBPaper00049574
CELE_F36A2.13Accession_evidenceNDBBX284601
Public_nameubr-5
DB_infoDatabaseAceViewgene1J404
WormQTLgeneWBGene00009460
WormFluxgeneWBGene00009460
NDBlocus_tagCELE_F36A2.13
PanthergeneCAEEL|WormBase=WBGene00009460|UniProtKB=G5EDT9
familyPTHR46276
NCBIgene172697
RefSeqproteinNM_059988.6
TREEFAMTREEFAM_IDTF314406
TrEMBLUniProtAccG5EDT9
UniProt_GCRPUniProtAccG5EDT9
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Oct 2014 12:51:06WBPerson2970EventAcquires_mergeWBGene00004934
Name_changeCGC_nameubr-5
304 Nov 2016 15:58:40WBPerson2970Name_changeOther_namesog-1
Acquires_mergeWBGene00004934
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classubr
Allele (132)
Legacy_information[Maine EM] Recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. Other alleles exhibit complex non-allelic non-complementation with mutations of other sog genes.
[C.elegansII] q305 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. Other alleles exhibit complex non-allelic non-complementation with mutations of other sog genes. OA1: q298 [Maine and Kimble 1993; EL]
Complementation_data[Maine EM] Fails to complement 6 other sog-1 alleles, complements mutations of other sog genes.
StrainWBStrain00022531
WBStrain00031823
RNASeq_FPKM (74)
GO_annotation00014757
00014758
00014759
00014760
00014761
00014762
00014763
00117120
00117121
00117122
Ortholog (56)
ParalogWBGene00016650Caenorhabditis elegansFrom_analysisTreeFam
WBGene00003898Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007009Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008429Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00009738Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016405Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017782Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021685Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022069Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022358Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionF36A2.13 encodes an E3 ubiquitin ligase similar to the mammalian UBR5 ubiquitin ligases; F36A2.13 is predicted to function in ubiquitin-dependent protein catabolic processes.Curator_confirmedWBPerson1843
Date_last_updated18 Jul 2014 00:00:00
Automated_descriptionPredicted to enable ubiquitin-ubiquitin ligase activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway and protein polyubiquitination. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in carcinoma (multiple) and invasive ductal carcinoma. Is an ortholog of human UBR5 (ubiquitin protein ligase E3 component n-recognin 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:3008Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:234Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:10534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:3717Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:4948Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:2600Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16806)
Molecular_infoCorresponding_CDSF36A2.13
Corresponding_transcriptF36A2.13.1
F36A2.13.2
Other_sequence (42)
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00084251Inferred_automaticallyRNAi_primary
WBRNAi00094647Inferred_automaticallyRNAi_primary
WBRNAi00076380Inferred_automaticallyRNAi_primary
WBRNAi00046441Inferred_automaticallyRNAi_primary
WBRNAi00003602Inferred_automaticallyRNAi_primary
Expr_patternExpr1022573
Expr1034143
Expr1150310
Expr2017729
Expr2035867
Drives_constructWBCnstr00032166
Construct_productWBCnstr00032166
Microarray_results (21)
Expression_cluster (149)
Interaction (47)
Map_infoMapIPosition3.21396
PositivePositive_cloneF36A2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point2000
2001
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene