WormBase Tree Display for Gene: WBGene00007772
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WBGene00007772 | SMap | S_parent | Sequence | C27C12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | egrh-1 | Person_evidence | WBPerson460 | |||||
Sequence_name | C27C12.2 | ||||||||
Molecular_name | C27C12.2 | ||||||||
C27C12.2.1 | |||||||||
CE40601 | |||||||||
Other_name | CELE_C27C12.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | egrh-1 | ||||||||
DB_info | Database | AceView | gene | XP467 | |||||
WormQTL | gene | WBGene00007772 | |||||||
WormFlux | gene | WBGene00007772 | |||||||
NDB | locus_tag | CELE_C27C12.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00007772|UniProtKB=Q18250 | |||||||
family | PTHR23235 | ||||||||
NCBI | gene | 181580 | |||||||
RefSeq | protein | NM_078061.6 | |||||||
SwissProt | UniProtAcc | Q18250 | |||||||
TREEFAM | TREEFAM_ID | TF318980 | |||||||
UniProt_GCRP | UniProtAcc | Q18250 | |||||||
OMIM | gene | 129010 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 26 Mar 2007 13:57:19 | WBPerson2970 | Name_change | CGC_name | egrh-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | egrh | ||||||||
Allele (58) | |||||||||
Strain | WBStrain00029951 | ||||||||
WBStrain00051977 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (36) | |||||||||
Paralog | WBGene00003480 | Caenorhabditis elegans | From_analysis | Panther | |||||
WBGene00018990 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00009998 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00043705 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00009743 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00012735 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00044651 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | egrh-1 encodes a zinc finger protein that has similarity to the vertebrate EGR (early growth response factor) family of proteins, including the human EGR transcription factors; in C. elegans, EGRH-1 activity is required, non-autonomously in the gut and the somatic gonad, for regulation of oocyte meiotic maturation and ovulation; EGRH-1 is expressed in the somatic gonad, specifically in the gonadal sheath and distal tip cells, and in sperm, as well as in the gut, and other non-gonadal tissues. | Paper_evidence | WBPaper00037082 | |||||
Curator_confirmed | WBPerson12884 | ||||||||
WBPerson1843 | |||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 12 Jan 2015 00:00:00 | ||||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of oocyte maturation and negative regulation of ovulation. Located in nucleus and perinuclear region of cytoplasm. Expressed in body wall musculature; hermaphrodite somatic gonadal cell; nervous system; pharynx; and sperm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); lung disease (multiple); and neuropathy (multiple). Is an ortholog of human EGR1 (early growth response 1) and EGR3 (early growth response 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (19) | ||||||||
Molecular_info | Corresponding_CDS | C27C12.2 | |||||||
Corresponding_transcript | C27C12.2.1 | ||||||||
Other_sequence (22) | |||||||||
Associated_feature (14) | |||||||||
Transcription_factor | WBTranscriptionFactor000963 | ||||||||
Experimental_info | RNAi_result | WBRNAi00092959 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00029263 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00110186 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076168 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00041323 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00110187 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00110188 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00011248 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00114391 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00070166 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr9107 | ||||||||
Expr1017133 | |||||||||
Expr1033368 | |||||||||
Expr1145368 | |||||||||
Expr2011234 | |||||||||
Expr2029470 | |||||||||
Drives_construct | WBCnstr00008304 | ||||||||
WBCnstr00008305 | |||||||||
Construct_product | WBCnstr00008304 | ||||||||
Antibody | WBAntibody00002152 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (136) | |||||||||
Interaction (21) | |||||||||
Anatomy_function | WBbtf0409 | ||||||||
WBbtf0410 | |||||||||
WBbtf0411 | |||||||||
WBbtf1061 | |||||||||
Map_info | Map | X | Position | 21.4389 | Error | 0.005794 | |||
Positive | Positive_clone | C27C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027882 | ||||||||
WBPaper00032994 | |||||||||
WBPaper00037082 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00061738 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |