WormBase Tree Display for Gene: WBGene00009998
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| WBGene00009998 | SMap | S_parent | Sequence | F53F8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | klf-2 | Person_evidence | WBPerson4368 | |||||
| Sequence_name | F53F8.1 | ||||||||
| Molecular_name | F53F8.1 | ||||||||
| F53F8.1.1 | |||||||||
| CE44073 | |||||||||
| F53F8.1.2 | |||||||||
| Other_name | CELE_F53F8.1 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | klf-2 | ||||||||
| DB_info | Database | AceView | gene | 5V159 | |||||
| WormQTL | gene | WBGene00009998 | |||||||
| WormFlux | gene | WBGene00009998 | |||||||
| NDB | locus_tag | CELE_F53F8.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00009998|UniProtKB=O62259 | |||||||
| family | PTHR23235 | ||||||||
| NCBI | gene | 186179 | |||||||
| RefSeq | protein | NM_075594.4 | |||||||
| SwissProt | UniProtAcc | O62259 | |||||||
| UniProt_GCRP | UniProtAcc | O62259 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 23 May 2008 16:29:58 | WBPerson2970 | Name_change | CGC_name | klf-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | klf | ||||||||
| Allele (62) | |||||||||
| Strain | WBStrain00031785 | ||||||||
| WBStrain00051946 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00037553 | ||||||||
| 00037554 | |||||||||
| 00037555 | |||||||||
| 00037556 | |||||||||
| 00037557 | |||||||||
| 00037558 | |||||||||
| 00037559 | |||||||||
| 00037560 | |||||||||
| 00037561 | |||||||||
| Ortholog (31) | |||||||||
| Paralog | WBGene00003480 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00007772 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00009743 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018990 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00043705 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00012735 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00011926 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | klf-2 encodes one of three C. elegans Kruppel-like transcription factors; KLF-2 is homologous to human WT1, which when mutated leads to Wilms tumour (OMIM:194070). | Paper_evidence | WBPaper00004103 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of gene expression and regulation of lipid metabolic process. Predicted to be located in nucleus. Expressed in intestine. Human ortholog(s) of this gene implicated in intracranial aneurysm. Is an ortholog of human KLF5 (KLF transcription factor 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10941 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6349) | ||||
| Molecular_info | Corresponding_CDS | F53F8.1 | |||||||
| Corresponding_CDS_history | F53F8.1:wp205 | ||||||||
| Corresponding_transcript | F53F8.1.1 | ||||||||
| F53F8.1.2 | |||||||||
| Other_sequence | Dviv_isotig03145 | ||||||||
| Dviv_isotig03140 | |||||||||
| Dviv_isotig03142 | |||||||||
| TM01186 | |||||||||
| XI03428 | |||||||||
| Dviv_isotig03138 | |||||||||
| TMC00774_1 | |||||||||
| Dviv_isotig03136 | |||||||||
| XIC03020_1 | |||||||||
| Associated_feature | WBsf647752 | ||||||||
| WBsf647753 | |||||||||
| WBsf662266 | |||||||||
| WBsf662267 | |||||||||
| WBsf978723 | |||||||||
| WBsf1003615 | |||||||||
| WBsf1003616 | |||||||||
| WBsf1021995 | |||||||||
| WBsf233213 | |||||||||
| Transcription_factor | WBTranscriptionFactor000233 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00078332 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00015532 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076465 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048160 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr13327 | ||||||||
| Expr13328 | |||||||||
| Expr1014958 | |||||||||
| Expr1151972 | |||||||||
| Expr2012951 | |||||||||
| Expr2031183 | |||||||||
| Drives_construct | WBCnstr00031752 | ||||||||
| WBCnstr00039203 | |||||||||
| Construct_product | WBCnstr00031752 | ||||||||
| WBCnstr00039203 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (100) | |||||||||
| Interaction (147) | |||||||||
| Map_info | Map | V | Position | 25.0351 | Error | 0.000795 | |||
| Positive | Positive_clone | F53F8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
