WormBase Tree Display for Gene: WBGene00007549

WBGene00007549 SMap: S_parent: Sequence: C13C4
  Identity: Version: 2
    Name: CGC_name: spin-1 Paper_evidence: WBPaper00042308
      Sequence_name: C13C4.5
      Molecular_name: C13C4.5
        C13C4.5.1
        CE08130
      Other_name: CELE_C13C4.5 Accession_evidence: NDB BX284605
      Public_name: spin-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Jun 2013 14:47:04 WBPerson2970 Name_change: CGC_name: spin-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spin
    Allele (23)
    Strain: WBStrain00002087
      WBStrain00032371
    RNASeq_FPKM (74)
    GO_annotation: 00026210
      00026211
      00026212
      00115658
      00115659
    Ortholog (45)
    Paralog: WBGene00008033 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013739 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00008598 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 115. Is an ortholog of human SPNS1 (SPNS lysolipid transporter 1, lysophospholipid); SPNS2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate); and SPNS3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111643 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:26992)
  Molecular_info: Corresponding_CDS: C13C4.5
    Corresponding_transcript: C13C4.5.1
    Other_sequence (39)
    Associated_feature: WBsf661858
      WBsf717265
      WBsf232605
      WBsf232606
  Experimental_info: RNAi_result: WBRNAi00090667 Inferred_automatically: RNAi_primary
      WBRNAi00066581 Inferred_automatically: RNAi_primary
      WBRNAi00010683 Inferred_automatically: RNAi_primary
      WBRNAi00040434 Inferred_automatically: RNAi_primary
      WBRNAi00102256 Inferred_automatically: RNAi_primary
      WBRNAi00028842 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1109
      Chronogram1192
      Expr5253
      Expr5254
      Expr1011912
      Expr1033247
      Expr1144499
      Expr2016057
      Expr2034292
    Drives_construct: WBCnstr00002249
      WBCnstr00004270
      WBCnstr00033655
    Construct_product: WBCnstr00033655
    Microarray_results (19)
    Expression_cluster: WBPaper00029359_1183
      WBPaper00029359_1280
      WBPaper00029359_1310
      WBPaper00029359_1362
      WBPaper00029359_1364
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1578
      WBPaper00029359_1604
      WBPaper00029359_1636
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035211:age-1_vs_N2_downregulated
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041071:spe-44_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Spermatogenic
      WBPaper00048988:neuron_expressed
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00054192:cold-shock_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:sperm_expressed
      WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:hyp7_AB_lineage
      WBPaper00061340:P_cell
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:saeg-1_18803-mpz-2_15880
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062590:Aging_downregulated_body-wall-muscle
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_downregulated_N2_protein
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064502:nhr-23(kry61);spe-44(fx110)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:11_1
      WBPaper00065841:30_1
      WBPaper00065841:30_4
      WBPaper00065841:102_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      cgc4489_group_25
      WBPaper00026980:intestine_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_C
      WBPaper00037695:WC_5-day
      WBPaper00040184:hcf-1down_sir-2.1up_daf-2nc
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotype_environment_interaction
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecium_downregulated
      [cgc6390]:Cluster_D
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction: WBInteraction000028558
      WBInteraction000033672
      WBInteraction000277018
      WBInteraction000373452
      WBInteraction000408472
      WBInteraction000408606
      WBInteraction000543492
      WBInteraction000580543
  Map_info: Map: V Position: 3.6627
    Positive: Positive_clone: C13C4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042308
    WBPaper00055090
    WBPaper00062728
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene