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WormBase Tree Display for Gene: WBGene00006824

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Name Class

WBGene00006824EvidencePaper_evidenceWBPaper00019431
SMapS_parentSequenceY105E8A
IdentityVersion1
NameCGC_nameunc-95Person_evidenceWBPerson261
Sequence_nameY105E8A.6
Molecular_nameY105E8A.6
Y105E8A.6.1
CE31857
Other_nameY105E8E.eCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y105E8A.6Accession_evidenceNDBBX284601
Public_nameunc-95
DB_infoDatabaseAceViewgene1O974
WormQTLgeneWBGene00006824
WormFluxgeneWBGene00006824
NDBlocus_tagCELE_Y105E8A.6
NCBIgene173301
RefSeqproteinNM_170938.7
SwissProtUniProtAccQ9NEZ5
UniProt_GCRPUniProtAccQ9NEZ5
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
AlleleWBVar00248845
WBVar00691522
WBVar00691523
WBVar00691524
WBVar00691525
WBVar00691526
WBVar00691527
WBVar00691528
WBVar00691529
WBVar00691530
WBVar00691531
WBVar00691532
WBVar00691533
WBVar00691534
WBVar00691535
WBVar00691536
WBVar00691537
WBVar00691538
WBVar00691539
WBVar00691540
WBVar01714959
WBVar01714960
WBVar01714961
WBVar01499739
WBVar00253081
WBVar01289914
WBVar01289915
WBVar01289916
WBVar00352380
WBVar00352381
WBVar00352382
WBVar00352383
WBVar00352384
WBVar00352385
WBVar00352386
WBVar00352387
WBVar00352388
WBVar00352389
WBVar00352390
WBVar01499999
WBVar01412228
WBVar01412229
WBVar00252398
WBVar01499823
WBVar00248842
WBVar01498939
WBVar00161954
WBVar00161955
WBVar00161956
WBVar00161957
WBVar00161958
WBVar00161959
WBVar00161960
WBVar02129061
WBVar00691514
WBVar00691515
WBVar00691516
WBVar01574533
WBVar00691517
WBVar00691518
WBVar00092167
WBVar00691519
WBVar00691520
WBVar00691521
WBVar01502459
Legacy_informationsu106sd : very slow or paralysed Egl; abnormal variable muscle birefringence disorganized sarcomeres with collections of thin filaments. ES3. NA4 (su33amber (simialr phenotypes ME0) etc.).
[C.elegansII] su106sd : very slow or paralysed, Egl; abnormal variable muscle birefringence, disorganized sarcomeres with collections of thin filaments. ES3. OA3: su33amb (similar phenotypes, ME0), etc. [Zengel and Epstein 1980; HE]
StrainWBStrain00035931
WBStrain00008387
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (29)
ParalogWBGene00000438Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00002987Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00002988Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00003000Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00003167Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006654Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00015216Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017644Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022518Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionunc-95 encodes a LIM domain-containing protein related to Drosophila and vertebrate paxillins; UNC-95 is required for locomotion and organization of thick and thin filaments in body wall muscle; by homology, UNC-95 may function as an anchor protein that links signaling and cytoskeletal proteins at focal adhesions; in vitro, UNC-95 interacts with RNF-5, a RING finger protein that may function as an E3 ligase to regulate UNC-95 levels via ubiquitin-mediated degradation; UNC-95 is expressed in body-wall and vulval muscles, and co-localizes with RNF-5 to muscle dense bodies (focal adhesion-like attachment sites).Paper_evidence (3)
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables protein domain specific binding activity. Located in M band; nucleus; and striated muscle dense body.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY105E8A.6
Corresponding_CDS_historyY105E8A.6:wp86
Corresponding_transcriptY105E8A.6.1
Other_sequence (34)
Associated_featureWBsf649756
WBsf665123
WBsf979068
WBsf986146
WBsf986147
WBsf1011238
WBsf220605
WBsf220606
WBsf220607
WBsf220608
Transcription_factorWBTranscriptionFactor000438
Experimental_infoRNAi_result (13)
Expr_patternExpr2991
Expr2992
Expr8314
Expr8542
Expr1012404
Expr1032888
Expr1158771
Expr2017921
Expr2036057
Drives_constructWBCnstr00006034
WBCnstr00011070
WBCnstr00011071
WBCnstr00013356
WBCnstr00034135
Construct_productWBCnstr00006034
WBCnstr00013356
WBCnstr00034135
Regulate_expr_clusterWBPaper00031097:unc-95(su33)_upregulated
AntibodyWBAntibody00001286
Microarray_results (18)
Expression_cluster (157)
Interaction (56)
WBProcessWBbiopr:00000006
Map_infoMapIPosition24.674Error0.00615
Well_ordered
PositivePositive_cloneY105E8AInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point392
393
394
3684
3685
7080
Multi_point2332
4894
Pos_neg_data5109
5110
5111
5112
5113
5114
5115
Reference (31)
MethodGene