WormBase Tree Display for Gene: WBGene00006784

WBGene00006784 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: T21C12
  Identity: Version: 1
    Name: CGC_name: unc-49 Person_evidence: WBPerson261
      Sequence_name: T21C12.1
      Molecular_name (40)
      Other_name: unc-49A Accession_evidence: EMBL AF151640
        unc-49B Accession_evidence: EMBL AF151641
        unc-49C Accession_evidence: EMBL AF151644
        CELE_T21C12.1 Accession_evidence: NDB BX284603
      Public_name: unc-49
    DB_info: Database: AceView gene 3L621
        WormQTL gene WBGene00006784
        WormFlux gene WBGene00006784
        NDB locus_tag CELE_T21C12.1
        Panther gene CAEEL|WormBase=WBGene00006784|UniProtKB=G5ECD3
          family PTHR18945
        NCBI gene 176472
        RefSeq protein (13)
        TrEMBL UniProtAcc (13)
        UniProt_GCRP UniProtAcc G5ECD3
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:42 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:1826 Homo sapiens Paper_evidence: WBPaper00060194
          Curator_confirmed: WBPerson324
          Date_last_updated: 18 May 2022 00:00:00
  Models_disease_asserted: WBDOannot00001202
    WBDOannot00001203
  Molecular_info: Corresponding_CDS (13)
    Corresponding_CDS_history: T21C12.1a:wp227
      T21C12.1a:wp239
      T21C12.1g:wp275
    Corresponding_transcript (14)
    Other_sequence (51)
    Associated_feature (25)
  Experimental_info: RNAi_result: WBRNAi00090257 Inferred_automatically: RNAi_primary
      WBRNAi00053708 Inferred_automatically: RNAi_primary
      WBRNAi00089728 Inferred_automatically: RNAi_primary
      WBRNAi00066348 Inferred_automatically: RNAi_primary
      WBRNAi00027895 Inferred_automatically: RNAi_primary
      WBRNAi00000954 Inferred_automatically: RNAi_primary
      WBRNAi00090099 Inferred_automatically: RNAi_primary
      WBRNAi00018961 Inferred_automatically: RNAi_primary
      WBRNAi00089939 Inferred_automatically: RNAi_primary
      WBRNAi00006214 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1283
      Expr15907
      Expr1027570
      Expr1032855
      Expr1157259
      Expr1200291
      Expr2017881
      Expr2036017
      Marker2
      Marker19
    Drives_construct: WBCnstr00001626
      WBCnstr00001627
      WBCnstr00006881
      WBCnstr00010191
      WBCnstr00019381
      WBCnstr00020581
      WBCnstr00034153
      WBCnstr00042588
    Construct_product: WBCnstr00001627
      WBCnstr00006881
      WBCnstr00016180
      WBCnstr00019381
      WBCnstr00020010
      WBCnstr00020581
      WBCnstr00021428
      WBCnstr00034153
    Antibody: WBAntibody00000613
      WBAntibody00001987
    Microarray_results (88)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037946:EGL-5_interacting
      WBPaper00038061:aldicarb_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045861:ash-2(tm1095)_upregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049626:UNC-75_target
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050094:mes-2(bn11)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056586:kri-1(ok1251);mpk-2(ok219)_downregulated
      WBPaper00056586:kri-1(ok1251)_downregulated
      WBPaper00056586:mpk-2(ok219)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_far_posterior
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:176662_at-Y53F4B.16
      WBPaper00061527:myo-3-Y71G12B.11_22540
      WBPaper00061527:syd-1_2945-unc-41_2170
      WBPaper00061651:MI_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:4_0
      WBPaper00065841:6_0
      WBPaper00065841:6_2
      WBPaper00065841:10_0
      WBPaper00065841:38_2
      WBPaper00065841:51_0
      WBPaper00065841:51_1
      WBPaper00065841:76_0
      WBPaper00065841:98_0
      WBPaper00065841:102_0
      WBPaper00065841:103_0
      WBPaper00065841:115_0
      WBPaper00065841:133_0
      WBPaper00065841:136_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_3
      cgc4489_group_20
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:TA300_up
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00042548:miRISC_enriched
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_A
    Interaction (31)
    WBProcess: WBbiopr:00000010
  Map_info: Map: III Position: 3.35021 Error: 0.089636
    Well_ordered
    Positive: Inside_rearr: nDf40
        mT1
      Positive_clone: T21C12 Person_evidence: WBPerson39
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 73
        86
        589
        3249
      Multi_point (55)
      Pos_neg_data: 3242
        3250
        3251
  Reference (138)
  Remark: Sequence connection from [Bamber BA]
  Method: Gene