WormBase Tree Display for Gene: WBGene00006592
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| WBGene00006592 | SMap | S_parent | Sequence | R151 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dpy-31 | Paper_evidence | WBPaper00024637 | |||||
| Sequence_name | R151.5 | ||||||||
| Molecular_name | R151.5a | ||||||||
| R151.5a.1 | |||||||||
| CE27200 | |||||||||
| R151.5a.2 | |||||||||
| R151.5b | |||||||||
| Other_name | nas-35 | CGC_data_submission | |||||||
| toh-2 | Paper_evidence | WBPaper00024637 | |||||||
| Person_evidence | WBPerson465 | ||||||||
| CELE_R151.5 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | dpy-31 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 13 Jun 2005 09:49:17 | WBPerson2970 | Name_change | CGC_name | dpy-31 | ||||
| Other_name | toh-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dpy | ||||||||
| Allele (80) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes protein with BMP-1 similarity. [LT] | ||||||||
| Strain | WBStrain00002101 | ||||||||
| WBStrain00002309 | |||||||||
| WBStrain00004667 | |||||||||
| WBStrain00004681 | |||||||||
| WBStrain00004687 | |||||||||
| WBStrain00004688 | |||||||||
| WBStrain00004691 | |||||||||
| WBStrain00004697 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (31) | |||||||||
| Paralog (48) | |||||||||
| Structured_description | Concise_description | dpy-31 encodes an astacin zinc-metalloprotease of the BMP-1 (bone morphogenetic protein-1)/TOLLOID family; dpy-31 activity is required for proper cuticle formation and thus for normal body morphology; in addition, dpy-31 is essential for embryonic and larval development at 25 degrees C; genetic and immunofluorescence studies suggest that DPY-31 functions as an endopeptidase that is required for processing, and ultimately proper extracellular assembly, of the SQT-3 cuticle collagen; dpy-31 is expressed in most hypodermal cells, with the exception of larval stage seam cells, throughout the life cycle with particularly strong expression seen during embryonic and larval stages; dpy-31 is also expressed in some head neurons, the amphid socket cells, rectal epithelial cells, and vulval epithelial cells in L4 larvae and adults. | Paper_evidence | WBPaper00024637 | |||||
| WBPaper00027067 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 08 Aug 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in extracellular region. Expressed in several structures, including amphid sheath cell; excretory duct; hypodermis; socket cell; and vulva. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R151.5a | |||||||
| Corresponding_CDS_history | R151.5b:wp248 | ||||||||
| Corresponding_transcript | R151.5b | ||||||||
| R151.5a.1 | |||||||||
| R151.5a.2 | |||||||||
| Other_sequence (44) | |||||||||
| Associated_feature | WBsf659160 | ||||||||
| WBsf716743 | |||||||||
| WBsf992958 | |||||||||
| WBsf225211 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00089138 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00061425 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061415 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005194 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017871 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051977 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061424 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct | WBCnstr00002877 | ||||||||
| WBCnstr00002878 | |||||||||
| WBCnstr00004447 | |||||||||
| WBCnstr00011166 | |||||||||
| WBCnstr00013625 | |||||||||
| WBCnstr00015220 | |||||||||
| WBCnstr00020247 | |||||||||
| WBCnstr00020355 | |||||||||
| WBCnstr00034283 | |||||||||
| Construct_product | WBCnstr00011166 | ||||||||
| WBCnstr00013625 | |||||||||
| WBCnstr00016573 | |||||||||
| WBCnstr00034283 | |||||||||
| Antibody | WBAntibody00002061 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (177) | |||||||||
| Interaction | WBInteraction000004828 | ||||||||
| WBInteraction000005319 | |||||||||
| WBInteraction000005375 | |||||||||
| WBInteraction000052808 | |||||||||
| WBInteraction000052809 | |||||||||
| WBInteraction000579000 | |||||||||
| Map_info | Map | III | Position | -0.771 | |||||
| Positive | Positive_clone | R151 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5431 | |||||||
| 4146 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (25) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.771285) | |||||||||
| Method | Gene |
