WormBase Tree Display for Gene: WBGene00006592
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WBGene00006592 | SMap | S_parent | Sequence | R151 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | dpy | |||||
Allele (80) | ||||||
Legacy_information | [C.elegansII] NMK. Encodes protein with BMP-1 similarity. [LT] | |||||
Strain | WBStrain00002101 | |||||
WBStrain00002309 | ||||||
WBStrain00004667 | ||||||
WBStrain00004681 | ||||||
WBStrain00004687 | ||||||
WBStrain00004688 | ||||||
WBStrain00004691 | ||||||
WBStrain00004697 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (14) | ||||||
Ortholog (31) | ||||||
Paralog (48) | ||||||
Structured_description | Concise_description | dpy-31 encodes an astacin zinc-metalloprotease of the BMP-1 (bone morphogenetic protein-1)/TOLLOID family; dpy-31 activity is required for proper cuticle formation and thus for normal body morphology; in addition, dpy-31 is essential for embryonic and larval development at 25 degrees C; genetic and immunofluorescence studies suggest that DPY-31 functions as an endopeptidase that is required for processing, and ultimately proper extracellular assembly, of the SQT-3 cuticle collagen; dpy-31 is expressed in most hypodermal cells, with the exception of larval stage seam cells, throughout the life cycle with particularly strong expression seen during embryonic and larval stages; dpy-31 is also expressed in some head neurons, the amphid socket cells, rectal epithelial cells, and vulval epithelial cells in L4 larvae and adults. | Paper_evidence | WBPaper00024637 | ||
WBPaper00027067 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 08 Aug 2006 00:00:00 | |||||
Automated_description | Predicted to enable metalloendopeptidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in extracellular region. Expressed in several structures, including amphid sheath cell; excretory duct; hypodermis; socket cell; and vulva. | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | R151.5a | ||||
Corresponding_CDS_history | R151.5b:wp248 | |||||
Corresponding_transcript | R151.5b | |||||
R151.5a.1 | ||||||
R151.5a.2 | ||||||
Other_sequence (44) | ||||||
Associated_feature | WBsf659160 | |||||
WBsf716743 | ||||||
WBsf992958 | ||||||
WBsf225211 | ||||||
Experimental_info | RNAi_result | WBRNAi00089138 | Inferred_automatically | RNAi_primary | ||
WBRNAi00061425 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00061415 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00005194 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00017871 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00051977 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00061424 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (13) | ||||||
Drives_construct | WBCnstr00002877 | |||||
WBCnstr00002878 | ||||||
WBCnstr00004447 | ||||||
WBCnstr00011166 | ||||||
WBCnstr00013625 | ||||||
WBCnstr00015220 | ||||||
WBCnstr00020247 | ||||||
WBCnstr00020355 | ||||||
WBCnstr00034283 | ||||||
Construct_product | WBCnstr00011166 | |||||
WBCnstr00013625 | ||||||
WBCnstr00016573 | ||||||
WBCnstr00034283 | ||||||
Antibody | WBAntibody00002061 | |||||
Microarray_results (25) | ||||||
Expression_cluster (177) | ||||||
Interaction | WBInteraction000004828 | |||||
WBInteraction000005319 | ||||||
WBInteraction000005375 | ||||||
WBInteraction000052808 | ||||||
WBInteraction000052809 | ||||||
WBInteraction000579000 | ||||||
Map_info | Map | III | Position | -0.771 | ||
Positive | Positive_clone | R151 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Mapping_data | Multi_point | 5431 | ||||
4146 | ||||||
Pseudo_map_position | ||||||
Reference (25) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.771285) | ||||||
Method | Gene |