WormBase Tree Display for Gene: WBGene00006586
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| WBGene00006586 | SMap | S_parent | Sequence | W03F8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tni-4 | Person_evidence | WBPerson300 | |||||
| Sequence_name | W03F8.1 | ||||||||
| Molecular_name | W03F8.1 | ||||||||
| W03F8.1.1 | |||||||||
| CE29829 | |||||||||
| Other_name | W03F8.b | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_W03F8.1 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | tni-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tni | ||||||||
| Allele (35) | |||||||||
| Strain | WBStrain00039806 | ||||||||
| WBStrain00047556 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00032901 | ||||||||
| 00032902 | |||||||||
| 00032903 | |||||||||
| 00032904 | |||||||||
| 00032905 | |||||||||
| 00032906 | |||||||||
| 00032907 | |||||||||
| 00114387 | |||||||||
| Ortholog (59) | |||||||||
| Paralog | WBGene00006584 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00006585 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006764 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | tni-4 encodes one of the four elegans troponin I proteins; tni-4 is required for the normal development of the pharynx during embryonic development; TNI-4 interacts only with the pharyngeal troponin C; tni-4 is expressed exclusively in the pharyngeal muscles. | Paper_evidence | WBPaper00025009 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 Jan 2007 00:00:00 | ||||||||
| Automated_description | Enables troponin C binding activity. Involved in embryo development and pharyngeal pumping. Located in sarcomere. Expressed in pharyngeal muscle cell and pharynx. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:397 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||
| DOID:0110313 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0111600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11946) | ||||||
| DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0111425 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0110459 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0080954 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11946) | ||||||
| DOID:0110460 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| Molecular_info | Corresponding_CDS | W03F8.1 | |||||||
| Corresponding_transcript | W03F8.1.1 | ||||||||
| Other_sequence (53) | |||||||||
| Associated_feature | WBsf047566 | ||||||||
| WBsf047567 | |||||||||
| WBsf645961 | |||||||||
| WBsf718087 | |||||||||
| WBsf996459 | |||||||||
| WBsf1017351 | |||||||||
| WBsf228269 | |||||||||
| WBsf228270 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00054697 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00036237 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077599 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078125 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001610 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2840 | ||||||||
| Expr4738 | |||||||||
| Expr4743 | |||||||||
| Expr1028427 | |||||||||
| Expr1032719 | |||||||||
| Expr1158235 | |||||||||
| Expr2017433 | |||||||||
| Expr2035572 | |||||||||
| Drives_construct | WBCnstr00012213 | ||||||||
| WBCnstr00034287 | |||||||||
| Construct_product | WBCnstr00034287 | ||||||||
| Antibody | WBAntibody00001012 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (168) | |||||||||
| Interaction (61) | |||||||||
| Map_info | Map | IV | Position | 1.5649 | Error | 0.001046 | |||
| Positive | Positive_clone | W03F8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Sequence connection from [Priest J, Allen TS]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
