WormBase Tree Display for Gene: WBGene00006508

WBGene00006508 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 4
    Name: CGC_name: tns-1 Person_evidence: WBPerson4023
      Sequence_name: M01E11.7
      Molecular_name (26)
      Other_name: tag-83 Person_evidence: WBPerson201
        tag-163 Person_evidence: WBPerson201
          Author_evidence
        CELE_M01E11.7 Accession_evidence: NDB BX284601
      Public_name: tns-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 30 Oct 2015 16:57:17 WBPerson1983 Event: Acquires_merge: WBGene00044422
        3 30 Oct 2015 16:57:17 WBPerson1983 Event: Acquires_merge: WBGene00006456
        4 05 Nov 2015 11:56:49 WBPerson2970 Name_change: CGC_name: tns-1
                Other_name: tag-163
      Acquires_merge: WBGene00006456
        WBGene00044422
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tns
    Allele (233)
    Strain: WBStrain00001427
      WBStrain00037181
      WBStrain00035750
      WBStrain00035825
      WBStrain00037455
      WBStrain00055333
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (57)
    Paralog: WBGene00020867 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable protein tyrosine phosphatase activity. Involved in positive regulation of axon regeneration. Located in axon. Expressed in DD neuron; VD neuron; head; and intestinal muscle. Is an ortholog of human TNS1 (tensin 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: M01E11.7a
      M01E11.7b
      M01E11.7c
      M01E11.7d
      M01E11.7e
      M01E11.7f
      M01E11.7g
      M01E11.7h
    Corresponding_CDS_history: M01E11.7a:wp251
    Corresponding_transcript: M01E11.7a.1
      M01E11.7b.1
      M01E11.7c.1
      M01E11.7c.2
      M01E11.7c.3
      M01E11.7d.1
      M01E11.7e.1
      M01E11.7f.1
      M01E11.7g.1
      M01E11.7h.1
    Other_sequence (36)
    Associated_feature (26)
  Experimental_info: RNAi_result: WBRNAi00109239 Inferred_automatically: RNAi_primary
      WBRNAi00050758 Inferred_automatically: RNAi_primary
      WBRNAi00047532 Inferred_automatically: RNAi_primary
      WBRNAi00109336 Inferred_automatically: RNAi_primary
      WBRNAi00109433 Inferred_automatically: RNAi_primary
      WBRNAi00004009 Inferred_automatically: RNAi_primary
      WBRNAi00109627 Inferred_automatically: RNAi_primary
      WBRNAi00109530 Inferred_automatically: RNAi_primary
      WBRNAi00003685 Inferred_automatically: RNAi_primary
      WBRNAi00034355 Inferred_automatically: RNAi_primary
    Expr_pattern (16)
    Drives_construct: WBCnstr00002135
      WBCnstr00003559
      WBCnstr00004229
      WBCnstr00037893
      WBCnstr00041423
    Construct_product: WBCnstr00013933
      WBCnstr00037893
    Microarray_results (74)
    Expression_cluster: WBPaper00029359_1291
      WBPaper00031040:Cluster_5
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046121:mesoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047132:skn-1(RNAi)_downregulated
      WBPaper00048952:glucose_induced
      WBPaper00048988:daf-16(mu86)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051461:pig-1(gm344)_downregulated
      WBPaper00052885:hrde-1(tm1200)-emb-4(qm31)_regulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:sod-2(ok1030)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056284:ints-1(RNAi)_downregulated
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057162:meg-3_meg-4_downregulated_sRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058942:henn-1(pk2295)_upregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060224:atf-6(ok551)_upregulated
      WBPaper00060526:plp-1(ok2155)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060871:M.humicola-extract_4h_regulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00061040:FW1256_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061340:mc1
      WBPaper00061340:mc2
      WBPaper00061340:mc3
      WBPaper00061340:mu_sph
      WBPaper00061340:Pharyngeal_intestinal_valve
      WBPaper00061340:pm6
      WBPaper00061340:pm8
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:176662_at-Y53F4B.16
      WBPaper00061527:saeg-1_18803-mpz-2_15880
      WBPaper00061651:DA9_enriched
      WBPaper00061651:PDA_enriched
      WBPaper00061651:PDB_enriched
      WBPaper00061651:PVD_enriched
      WBPaper00061651:VA12_enriched
      WBPaper00061818:ELKS-1_interacting
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064788:ketamine_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:hda-3(ok1991)_downregulated
      cgc4489_group_8
      cgc4489_group_21
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00027111:rde-3(ne298)_upregulated
      WBPaper00027111:rrf-2(ok210)_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00041174:environmental
      WBPaper00041174:genotype_environment_interaction
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045807:microcystin-LR_upregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_B
    Interaction (41)
  Map_info: Map: I Position: 0.246418
    Positive: Positive_clone: M01E11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4213
    Pseudo_map_position
  Reference: WBPaper00038444
    WBPaper00038491
    WBPaper00055090
    WBPaper00056803
    WBPaper00058449
    WBPaper00064400
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods.
  Method: Gene