WormBase Tree Display for Gene: WBGene00020867
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| WBGene00020867 | SMap | S_parent | Sequence | T27F7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | shc-2 | Paper_evidence | WBPaper00004558 | |||||
| Person_evidence | WBPerson842 | ||||||||
| WBPerson50 | |||||||||
| Sequence_name | T27F7.2 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_T27F7.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | shc-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 18 Oct 2006 16:47:14 | WBPerson2970 | Name_change | CGC_name | shc-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | shc | ||||||||
| Allele (275) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00006508 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | T27F7.2 encodes three proteins by multiple splicing, two of which (T27F7.2A-B) are fully orthologous to vertebrate Shc proteins (e.g., p52/p46SHC and p66SHC); like their orthologs, T27F7.2A-B have a PTB and an SH2 domain in N- to C-terminal order; T27F7.2 is expressed in gastrulating embryos (probably in neural precursors); T27F7.2 might be involved in RAS signal transduction or regulation of apoptosis. | Paper_evidence | WBPaper00004558 | |||||
| WBPaper00004651 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enriched in several structures, including ABalpapaap; excretory gland cell; g1; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SH2 domain superfamily and SH2 domain. Is an ortholog of human SH2D5 (SH2 domain containing 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T27F7.2a | |||||||
| T27F7.2b | |||||||||
| T27F7.2c | |||||||||
| Corresponding_CDS_history | T27F7.2a:wp227 | ||||||||
| T27F7.2b:wp227 | |||||||||
| Corresponding_transcript | T27F7.2a.1 | ||||||||
| T27F7.2b.1 | |||||||||
| T27F7.2b.2 | |||||||||
| T27F7.2c.1 | |||||||||
| T27F7.2c.2 | |||||||||
| Other_sequence (18) | |||||||||
| Associated_feature (31) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00054347 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00054348 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036052 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr417 | ||||||||
| Expr1011838 | |||||||||
| Expr1039096 | |||||||||
| Expr1157894 | |||||||||
| Expr2015807 | |||||||||
| Expr2034040 | |||||||||
| Microarray_results (34) | |||||||||
| Expression_cluster (158) | |||||||||
| Interaction | WBInteraction000304431 | ||||||||
| WBInteraction000383016 | |||||||||
| WBInteraction000448874 | |||||||||
| WBInteraction000543056 | |||||||||
| Map_info | Map | II | Position | -2.60871 | Error | 0.002114 | |||
| Positive | Positive_clone | T27F7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027580 | ||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
