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WormBase Tree Display for Gene: WBGene00006424

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Name Class

WBGene00006424SMapS_parentSequenceF49E10
IdentityVersion3
NameCGC_namectbp-1Person_evidenceWBPerson2627
Sequence_nameF49E10.5
Molecular_nameF49E10.5a
F49E10.5a.1
CE29966
F49E10.5b
CE47412
F49E10.5b.1
Other_nametag-45Person_evidenceWBPerson201
CELE_F49E10.5Accession_evidenceNDBBX284606
Public_namectbp-1
DB_infoDatabaseAceViewgeneXG491
WormQTLgeneWBGene00006424
WormFluxgeneWBGene00006424
NDBlocus_tagCELE_F49E10.5
PanthergeneCAEEL|WormBase=WBGene00006424|UniProtKB=Q20595
familyPTHR46029
NCBIgene180853
RefSeqproteinNM_001270102.3
NM_001270101.4
SwissProtUniProtAccQ20595
UniProt_GCRPUniProtAccQ20595
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
205 Oct 2006 15:31:09WBPerson2970EventAcquires_mergeWBGene00018642
316 Oct 2006 14:08:57WBPerson2970Name_changeCGC_namectbp-1
Other_nametag-45
Acquires_mergeWBGene00018642
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classctbp
Allele (175)
Possibly_affected_byWBVar02157252
StrainWBStrain00031454
WBStrain00030103
WBStrain00047496
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (40)
ParalogWBGene00007836Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionProvisional_descriptiontag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.Curator_confirmedWBPerson48
Concise_descriptiontag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
Automated_descriptionEnables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis and nervous system. Used to study alcohol use disorder. Is an ortholog of human CTBP1 (C-terminal binding protein 1) and CTBP2 (C-terminal binding protein 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:1574Homo sapiensPaper_evidenceWBPaper00041098
Curator_confirmedWBPerson324
Date_last_updated21 May 2019 00:00:00
Models_disease_assertedWBDOannot00000674
Molecular_infoCorresponding_CDSF49E10.5a
F49E10.5b
Corresponding_transcriptF49E10.5a.1
F49E10.5b.1
Other_sequence (24)
Associated_feature (20)
Transcription_factorWBTranscriptionFactor000823
Experimental_infoRNAi_resultWBRNAi00015304Inferred_automaticallyRNAi_primary
WBRNAi00103373Inferred_automaticallyRNAi_primary
WBRNAi00047836Inferred_automaticallyRNAi_primary
WBRNAi00015305Inferred_automaticallyRNAi_primary
WBRNAi00047835Inferred_automaticallyRNAi_primary
Expr_patternExpr11825
Expr12091
Expr12092
Expr12541
Expr1025813
Expr1032609
Expr1151670
Expr2010565
Expr2028805
Drives_constructWBCnstr00019349
WBCnstr00020016
WBCnstr00021742
WBCnstr00042043
WBCnstr00042044
Construct_productWBCnstr00019349
WBCnstr00020016
WBCnstr00020017
WBCnstr00021150
WBCnstr00021742
Microarray_results (25)
Expression_cluster (179)
Interaction (71)
WBProcessWBbiopr:00000121
Map_infoMapXPosition-4.16195Error0.01114
PositivePositive_cloneF49E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (26)
RemarkKilled due to lack of dataCurator_confirmedWBPerson2970
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene