WormBase Tree Display for Gene: WBGene00006424

WBGene00006424 SMap: S_parent: Sequence: F49E10
  Identity: Version: 3
    Name: CGC_name: ctbp-1 Person_evidence: WBPerson2627
      Sequence_name: F49E10.5
      Molecular_name: F49E10.5a
        F49E10.5a.1
        CE29966
        F49E10.5b
        CE47412
        F49E10.5b.1
      Other_name: tag-45 Person_evidence: WBPerson201
        CELE_F49E10.5 Accession_evidence: NDB BX284606
      Public_name: ctbp-1
    DB_info: Database: AceView gene XG491
        WormQTL gene WBGene00006424
        WormFlux gene WBGene00006424
        NDB locus_tag CELE_F49E10.5
        Panther gene CAEEL|WormBase=WBGene00006424|UniProtKB=Q20595
          family PTHR46029
        NCBI gene 180853
        RefSeq protein NM_001270102.3
            NM_001270101.4
        SwissProt UniProtAcc Q20595
        UniProt_GCRP UniProtAcc Q20595
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 05 Oct 2006 15:31:09 WBPerson2970 Event: Acquires_merge: WBGene00018642
        3 16 Oct 2006 14:08:57 WBPerson2970 Name_change: CGC_name: ctbp-1
                Other_name: tag-45
      Acquires_merge: WBGene00018642
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ctbp
    Allele (175)
    Possibly_affected_by: WBVar02157252
    Strain: WBStrain00031454
      WBStrain00030103
      WBStrain00047496
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (40)
    Paralog: WBGene00007836 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Provisional_description: tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase. Curator_confirmed: WBPerson48
      Concise_description: tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
      Automated_description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis and nervous system. Used to study alcohol use disorder. Is an ortholog of human CTBP1 (C-terminal binding protein 1) and CTBP2 (C-terminal binding protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00041098
          Curator_confirmed: WBPerson324
          Date_last_updated: 21 May 2019 00:00:00
  Models_disease_asserted: WBDOannot00000674
  Molecular_info: Corresponding_CDS: F49E10.5a
      F49E10.5b
    Corresponding_transcript: F49E10.5a.1
      F49E10.5b.1
    Other_sequence (24)
    Associated_feature (20)
    Transcription_factor: WBTranscriptionFactor000823
  Experimental_info (8)
  Map_info: Map: X Position: -4.16195 Error: 0.01114
    Positive: Positive_clone: F49E10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (26)
  Remark: Killed due to lack of data Curator_confirmed: WBPerson2970
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene