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WormBase Tree Display for Gene: WBGene00006363

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Name Class

WBGene00006363EvidencePaper_evidenceWBPaper00005543
SMapS_parentSequenceF35D2
IdentityVersion1
NameCGC_namesyd-1Person_evidenceWBPerson105
WBPerson293
Sequence_nameF35D2.5
Molecular_nameF35D2.5a
F35D2.5a.1
CE33391
F35D2.5c
CE33392
F35D2.5c.1
F35D2.5c.2
Other_nameCELE_F35D2.5Accession_evidenceNDBBX284602
Public_namesyd-1
DB_infoDatabaseAceViewgene2H876
WormQTLgeneWBGene00006363
WormFluxgeneWBGene00006363
NDBlocus_tagCELE_F35D2.5
PanthergeneCAEEL|WormBase=WBGene00006363|UniProtKB=Q86NH1
familyPTHR46150
NCBIgene174230
RefSeqproteinNM_001026975.4
NM_001383891.2
SwissProtUniProtAccQ86NH1
TREEFAMTREEFAM_IDTF323458
UniProt_GCRPUniProtAccQ86NH1
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsyd
AlleleWBVar00092787Inferred_automaticallyFrom strain object: RB1389
WBVar00088140
WBVar01499702
WBVar00744955
WBVar00744956
WBVar00744957
WBVar00744958
WBVar00744959
WBVar00744960
WBVar00744961
WBVar00744962
WBVar00744963
WBVar00744964
WBVar00744965
WBVar00744966
WBVar00744967
WBVar00744968
WBVar01498435
WBVar00744969
WBVar00088136
WBVar00744970
WBVar00744971
WBVar01474118
WBVar00744972
WBVar00744973
WBVar01241581
WBVar00744974
WBVar00744975
WBVar01241587
WBVar00744976
WBVar00744977
WBVar00744978
WBVar01949160
WBVar00744979
WBVar01949161
WBVar00744980
WBVar00744981
WBVar00744982
WBVar00744983
WBVar00744984
WBVar00088157
WBVar00744985
WBVar00744986
WBVar02002842
WBVar00744987
WBVar02002843
WBVar00744988
WBVar00744989
WBVar00744990
WBVar00744991
WBVar00744992
WBVar00744993
WBVar00744994
WBVar01720328
WBVar00744995
WBVar02018057
WBVar00744996
WBVar02018058
WBVar00744997
WBVar00744998
WBVar00744999
WBVar00745000
WBVar00745001
WBVar00745002
WBVar00259529
WBVar00259531
WBVar00259532
WBVar01375545
WBVar00173489
WBVar02130259
WBVar00173490
WBVar02130260
WBVar00225827
WBVar02151132
WBVar00225828
WBVar00370419
WBVar00370420
WBVar00370421
WBVar00370422
WBVar00370423
WBVar01438509
WBVar00370424
WBVar00370425
WBVar00370426
WBVar00146109
WBVar00370427
WBVar00370428
WBVar00370429
WBVar00370430
WBVar00370431
WBVar00370432
WBVar02150213
WBVar00370433
WBVar00370434
WBVar00370435
WBVar00370436
WBVar00370437
WBVar00370438
WBVar00370439
WBVar00370440
WBVar00600954
WBVar01413630
WBVar01666183
WBVar01666184
WBVar01666185
WBVar01497642
WBVar01784044
WBVar00551455
WBVar00551456
WBVar01498940
WBVar01308009
WBVar01308010
WBVar01308011
WBVar01308012
WBVar01308014
WBVar01308015
WBVar01308017
WBVar01308018
WBVar00276488
WBVar00276489
StrainWBStrain00032087
WBStrain00037967
WBStrain00005369
RNASeq_FPKM (74)
GO_annotation (23)
Ortholog (39)
ParalogWBGene00015267Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionsyd-1 encodes a protein that contains a Rho-GTPase-like activating domain as well as PDZ and C2 domains; during neuronal development, SYD-1 is required cell autonomously to positively regulate synaptogenesis; in regulating synapse development, SYD-1 functions as a positive regulator of SYD-2/liprin through direct interaction with ELKS-1, a pre-synaptic protein also required for synapse development; in turn, SYD-1 activity is regulated by RSY-1, a negative regulator of synaptogenesis, with which it also interacts physically; SYD-1 is expressed in neurons and localizes to presynaptic regions.Paper_evidenceWBPaper00005543
WBPaper00028808
Curator_confirmedWBPerson1843
Date_last_updated08 Mar 2010 00:00:00
Automated_descriptionEnables GTPase activator activity; Roundabout binding activity; and small GTPase binding activity. Involved in cell projection organization; cellular localization; and locomotion. Located in presynaptic membrane. Expressed in nerve ring and neurons. Is an ortholog of human SYDE2 (synapse defective Rho GTPase homolog 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF35D2.5a
F35D2.5c
Corresponding_CDS_historyF35D2.5:wp84
F35D2.5:wp92
F35D2.5b:wp93
F35D2.5b:wp274
Corresponding_transcriptF35D2.5a.1
F35D2.5c.1
F35D2.5c.2
Other_sequence (15)
Associated_feature (15)
Experimental_infoRNAi_resultWBRNAi00082910Inferred_automaticallyRNAi_primary
WBRNAi00046330Inferred_automaticallyRNAi_primary
WBRNAi00031774Inferred_automaticallyRNAi_primary
WBRNAi00014326Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00000711
WBCnstr00000728
WBCnstr00010752
WBCnstr00034391
Construct_productWBCnstr00000728
WBCnstr00007017
WBCnstr00010752
WBCnstr00010753
WBCnstr00012368
WBCnstr00012375
WBCnstr00018295
WBCnstr00021865
WBCnstr00034391
WBCnstr00038079
AntibodyWBAntibody00000569
Microarray_results (33)
Expression_cluster (201)
Interaction (51)
Map_infoMapIIPosition0.504817Error4.2e-05
PositivePositive_cloneF35D2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4188
4715
4733
5534
Pseudo_map_position
Reference (52)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene