Enriched in OLL; PVD; hermaphrodite distal tip cell; intestine; and male distal tip cell based on SAGE; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; mianserin; and D-glucose based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency; combined saposin deficiency; and late onset Parkinson's disease. Human PSAP enables several functions, including ganglioside binding activity; protein homodimerization activity; and scaffold protein binding activity. Is predicted to encode a protein with the following domains: Saposin B type, region 2; Saposin B type domain; Saposin-like type B, region 2; and Saposin-like. Is an ortholog of human PSAP (prosaposin).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.