WormBase Tree Display for Gene: WBGene00004918
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| WBGene00004918 | Evidence | Paper_evidence | WBPaper00005457 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK652 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | snr-5 | Person_evidence | WBPerson167 | |||||
| Sequence_name | ZK652.1 | ||||||||
| Molecular_name | ZK652.1 | ||||||||
| ZK652.1.1 | |||||||||
| CE00446 | |||||||||
| Other_name | CELE_ZK652.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | snr-5 | ||||||||
| DB_info | Database | AceView | gene | 3I953 | |||||
| WormQTL | gene | WBGene00004918 | |||||||
| WormFlux | gene | WBGene00004918 | |||||||
| NDB | locus_tag | CELE_ZK652.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004918|UniProtKB=P34659 | |||||||
| family | PTHR11021 | ||||||||
| NCBI | gene | 176103 | |||||||
| RefSeq | protein | NM_066307.7 | |||||||
| SwissProt | UniProtAcc | P34659 | |||||||
| TREEFAM | TREEFAM_ID | TF314481 | |||||||
| UniProt_GCRP | UniProtAcc | P34659 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | snr | ||||||||
| Allele | WBVar01500260 | ||||||||
| WBVar01499774 | |||||||||
| Strain | WBStrain00051877 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00003080 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | snr-5 encodes an ortholog of human small nuclear ribonucleoprotein SmF, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human SmE and SmG orthologs (snr-6 and snr-7, respectively), snr-5 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-5 is expressed in embryos and adult gonads. | Paper_evidence | WBPaper00005654 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 11 Jul 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of U1 snRNP; catalytic step 2 spliceosome; and pICln-Sm protein complex. Expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPF (small nuclear ribonucleoprotein polypeptide F). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9261 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11162) | ||||
| Molecular_info | Corresponding_CDS | ZK652.1 | |||||||
| Corresponding_transcript | ZK652.1.1 | ||||||||
| Other_sequence (74) | |||||||||
| Associated_feature | WBsf654935 | ||||||||
| WBsf225289 | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Chronogram734 | ||||||||
| Expr2229 | |||||||||
| Expr7238 | |||||||||
| Expr1012073 | |||||||||
| Expr1032447 | |||||||||
| Expr1163018 | |||||||||
| Expr2015969 | |||||||||
| Expr2034204 | |||||||||
| Drives_construct | WBCnstr00004145 | ||||||||
| WBCnstr00035322 | |||||||||
| Construct_product | WBCnstr00035322 | ||||||||
| Antibody | WBAntibody00000550 | ||||||||
| WBAntibody00000552 | |||||||||
| WBAntibody00000553 | |||||||||
| WBAntibody00000554 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (126) | |||||||||
| Interaction (202) | |||||||||
| Map_info | Map | III | Position | -0.534667 | Error | 0.000692 | |||
| Positive | Positive_clone | ZK652 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005457 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040897 | |||||||||
| WBPaper00046427 | |||||||||
| WBPaper00046572 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Locus was previously incorrectly associated with Y71G12B.14 [krb 030219] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
