WormBase Tree Display for Gene: WBGene00004918
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WBGene00004918 | Evidence | Paper_evidence | WBPaper00005457 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | ZK652 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | snr | ||||||
Allele | WBVar01500260 | ||||||
WBVar01499774 | |||||||
Strain | WBStrain00051877 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (36) | |||||||
Paralog | WBGene00003080 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
Structured_description | Concise_description | snr-5 encodes an ortholog of human small nuclear ribonucleoprotein SmF, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human SmE and SmG orthologs (snr-6 and snr-7, respectively), snr-5 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-5 is expressed in embryos and adult gonads. | Paper_evidence | WBPaper00005654 | |||
Curator_confirmed | WBPerson48 | ||||||
Date_last_updated | 11 Jul 2005 00:00:00 | ||||||
Automated_description | Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of U1 snRNP; catalytic step 2 spliceosome; and pICln-Sm protein complex. Expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPF (small nuclear ribonucleoprotein polypeptide F). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9261 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11162) | ||
Molecular_info | Corresponding_CDS | ZK652.1 | |||||
Corresponding_transcript | ZK652.1.1 | ||||||
Other_sequence (74) | |||||||
Associated_feature | WBsf654935 | ||||||
WBsf225289 | |||||||
Experimental_info | RNAi_result (23) | ||||||
Expr_pattern | Chronogram734 | ||||||
Expr2229 | |||||||
Expr7238 | |||||||
Expr1012073 | |||||||
Expr1032447 | |||||||
Expr1163018 | |||||||
Expr2015969 | |||||||
Expr2034204 | |||||||
Drives_construct | WBCnstr00004145 | ||||||
WBCnstr00035322 | |||||||
Construct_product | WBCnstr00035322 | ||||||
Antibody | WBAntibody00000550 | ||||||
WBAntibody00000552 | |||||||
WBAntibody00000553 | |||||||
WBAntibody00000554 | |||||||
Microarray_results (23) | |||||||
Expression_cluster (126) | |||||||
Interaction (202) | |||||||
Map_info | Map | III | Position | -0.534667 | Error | 0.000692 | |
Positive | Positive_clone | ZK652 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00005457 | ||||||
WBPaper00038491 | |||||||
WBPaper00040897 | |||||||
WBPaper00046427 | |||||||
WBPaper00046572 | |||||||
WBPaper00055090 | |||||||
Remark | Locus was previously incorrectly associated with Y71G12B.14 [krb 030219] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |