WormBase Tree Display for Gene: WBGene00004916
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| WBGene00004916 | Evidence | Paper_evidence | WBPaper00005457 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T28D9 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | snr-3 | Person_evidence | WBPerson167 | |||||
| Sequence_name | T28D9.10 | ||||||||
| Molecular_name | T28D9.10a | ||||||||
| T28D9.10a.1 | |||||||||
| CE02065 | |||||||||
| T28D9.10b | |||||||||
| CE51626 | |||||||||
| T28D9.10b.1 | |||||||||
| Other_name | CELE_T28D9.10 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | snr-3 | ||||||||
| DB_info | Database | AceView | gene | 2G778 | |||||
| WormQTL | gene | WBGene00004916 | |||||||
| WormFlux | gene | WBGene00004916 | |||||||
| NDB | locus_tag | CELE_T28D9.10 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004916|UniProtKB=Q10013 | |||||||
| family | PTHR23338 | ||||||||
| NCBI | gene | 174072 | |||||||
| RefSeq | protein | NM_062905.8 | |||||||
| NM_001330951.3 | |||||||||
| SwissProt | UniProtAcc | Q10013 | |||||||
| TrEMBL | UniProtAcc | M1ZJ32 | |||||||
| UniProt_GCRP | UniProtAcc | Q10013 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | snr | ||||||||
| Allele (13) | |||||||||
| Strain | WBStrain00037033 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00003078 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00004914 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00044916 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | snr-3 encodes an ortholog of human small nuclear ribonucleoprotein Sm D1, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm D2 ortholog (snr-4), snr-3 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-3 is expressed in embryos and adult gonads. | Paper_evidence | WBPaper00005457 | |||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 11 Jul 2005 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including nasopharynx carcinoma; nephritis; and systemic lupus erythematosus. Is an ortholog of human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9261 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11158) | ||||
| DOID:9074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11158) | ||||||
| DOID:576 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11158) | ||||||
| DOID:65 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11158) | ||||||
| DOID:10952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11158) | ||||||
| Molecular_info | Corresponding_CDS | T28D9.10a | |||||||
| T28D9.10b | |||||||||
| Corresponding_CDS_history | T28D9.10b:wp253 | ||||||||
| Corresponding_transcript | T28D9.10a.1 | ||||||||
| T28D9.10b.1 | |||||||||
| Other_sequence (51) | |||||||||
| Associated_feature | WBsf650149 | ||||||||
| WBsf223183 | |||||||||
| WBsf223184 | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr2229 | ||||||||
| Expr1020664 | |||||||||
| Expr1032445 | |||||||||
| Expr1157958 | |||||||||
| Expr2015967 | |||||||||
| Expr2034202 | |||||||||
| Drives_construct | WBCnstr00035324 | ||||||||
| Construct_product | WBCnstr00035324 | ||||||||
| Antibody | WBAntibody00000549 | ||||||||
| WBAntibody00000550 | |||||||||
| WBAntibody00000551 | |||||||||
| WBAntibody00000552 | |||||||||
| WBAntibody00000553 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (178) | |||||||||
| Interaction (204) | |||||||||
| Map_info | Map | II | Position | -0.218968 | Error | 0.002781 | |||
| Positive | Positive_clone | T28D9 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005457 | ||||||||
| WBPaper00027057 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00046572 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00063976 | |||||||||
| WBPaper00064663 | |||||||||
| Remark | Locus was previously incorrectly associated with C52E4.3. [krb 030219] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
