WormBase Tree Display for Gene: WBGene00003078
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| WBGene00003078 | Evidence | Person_evidence | WBPerson1846 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F32A5 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | lsm-4 | |||||||
| Sequence_name | F32A5.7 | ||||||||
| Molecular_name | F32A5.7 | ||||||||
| F32A5.7.1 | |||||||||
| CE01277 | |||||||||
| Other_name | CELE_F32A5.7 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | lsm-4 | ||||||||
| DB_info | Database | AceView | gene | 2H542 | |||||
| WormQTL | gene | WBGene00003078 | |||||||
| WormFlux | gene | WBGene00003078 | |||||||
| NDB | locus_tag | CELE_F32A5.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003078|UniProtKB=Q19952 | |||||||
| family | PTHR23338 | ||||||||
| NCBI | gene | 174193 | |||||||
| RefSeq | protein | NM_063113.7 | |||||||
| SwissProt | UniProtAcc | Q19952 | |||||||
| TREEFAM | TREEFAM_ID | TF315027 | |||||||
| UniProt_GCRP | UniProtAcc | Q19952 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lsm | ||||||||
| Allele | WBVar01499702 | ||||||||
| WBVar00094227 | |||||||||
| WBVar01498435 | |||||||||
| WBVar00173221 | |||||||||
| WBVar00173222 | |||||||||
| WBVar02146162 | |||||||||
| WBVar00743026 | |||||||||
| WBVar00743027 | |||||||||
| WBVar01498940 | |||||||||
| Strain | WBStrain00037541 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00044916 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00004916 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00004914 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | lsm-4 encodes a protein with similarity to the Sm-like LSM4 small nuclear ribonucleoproteins that are core components of the spliceosomal U6 small nuclear ribonucleoprotein complex; RNAi experiments indicate that lsm-4 is an essential gene required for development, growth, locomotion, body morphogenesis, and normal lifespan; about 5% to 20% of lsm-4 transcripts are RNA edited to change A to G resulting in a change to residue 13 from an N to a D. | Paper_evidence | WBPaper00045975 | |||||
| WBPaper00029258 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00031212 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson4025 | |||||||||
| Date_last_updated | 28 Dec 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable U6 snRNA binding activity. Predicted to be involved in P-body assembly and spliceosomal snRNP assembly. Located in cytoplasm and nucleus. Expressed in germ line and somatic cell. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1936 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17259) | ||||
| Molecular_info | Corresponding_CDS | F32A5.7 | |||||||
| Corresponding_transcript | F32A5.7.1 | ||||||||
| Associated_feature | WBsf650219 | ||||||||
| WBsf223318 | |||||||||
| Experimental_info | RNAi_result (31) | ||||||||
| Expr_pattern | Expr12402 | ||||||||
| Expr1010323 | |||||||||
| Expr1031453 | |||||||||
| Expr1149969 | |||||||||
| Expr2013291 | |||||||||
| Expr2031522 | |||||||||
| Drives_construct | WBCnstr00020675 | ||||||||
| WBCnstr00022516 | |||||||||
| WBCnstr00036245 | |||||||||
| Construct_product | WBCnstr00020675 | ||||||||
| WBCnstr00022516 | |||||||||
| WBCnstr00036245 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (72) | |||||||||
| Interaction (272) | |||||||||
| Map_info | Map | II | Position | 0.499911 | Error | 4.5e-05 | |||
| Positive | Positive_clone | F32A5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00046572 | |||||||||
| WBPaper00048178 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
