WormBase Tree Display for Gene: WBGene00004916

WBGene00004916 Evidence: Paper_evidence: WBPaper00005457
  SMap: S_parent: Sequence: T28D9
  Identity: Version: 1
    Name: CGC_name: snr-3 Person_evidence: WBPerson167
      Sequence_name: T28D9.10
      Molecular_name: T28D9.10a
        T28D9.10a.1
        CE02065
        T28D9.10b
        CE51626
        T28D9.10b.1
      Other_name: CELE_T28D9.10 Accession_evidence: NDB BX284602
      Public_name: snr-3
    DB_info: Database: AceView gene 2G778
        WormQTL gene WBGene00004916
        WormFlux gene WBGene00004916
        NDB locus_tag CELE_T28D9.10
        Panther gene CAEEL|WormBase=WBGene00004916|UniProtKB=Q10013
          family PTHR23338
        NCBI gene 174072
        RefSeq protein NM_062905.8
            NM_001330951.3
        SwissProt UniProtAcc Q10013
        TrEMBL UniProtAcc M1ZJ32
        UniProt_GCRP UniProtAcc Q10013
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: snr
    Allele (13)
    Strain: WBStrain00037033
    RNASeq_FPKM (74)
    GO_annotation (25)
    Ortholog (35)
    Paralog: WBGene00003078 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004914 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00044916 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: snr-3 encodes an ortholog of human small nuclear ribonucleoprotein Sm D1, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm D2 ortholog (snr-4), snr-3 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-3 is expressed in embryos and adult gonads. Paper_evidence: WBPaper00005457
          Curator_confirmed: WBPerson48
          Date_last_updated: 11 Jul 2005 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including nasopharynx carcinoma; nephritis; and systemic lupus erythematosus. Is an ortholog of human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9261 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11158)
      DOID:9074 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11158)
      DOID:576 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11158)
      DOID:65 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11158)
      DOID:10952 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11158)
  Molecular_info: Corresponding_CDS: T28D9.10a
      T28D9.10b
    Corresponding_CDS_history: T28D9.10b:wp253
    Corresponding_transcript: T28D9.10a.1
      T28D9.10b.1
    Other_sequence (51)
    Associated_feature: WBsf650149
      WBsf223183
      WBsf223184
  Experimental_info: RNAi_result (23)
    Expr_pattern: Expr2229
      Expr1020664
      Expr1032445
      Expr1157958
      Expr2015967
      Expr2034202
    Drives_construct: WBCnstr00035324
    Construct_product: WBCnstr00035324
    Antibody: WBAntibody00000549
      WBAntibody00000550
      WBAntibody00000551
      WBAntibody00000552
      WBAntibody00000553
    Microarray_results (22)
    Expression_cluster (178)
    Interaction: WBInteraction000008482
      WBInteraction000034323
      WBInteraction000035259
      WBInteraction000037227
      WBInteraction000037321
      WBInteraction000038081
      WBInteraction000038453
      WBInteraction000038454
      WBInteraction000038455
      WBInteraction000038456
      WBInteraction000038457
      WBInteraction000038458
      WBInteraction000039616
      WBInteraction000039958
      WBInteraction000040495
      WBInteraction000040497
      WBInteraction000040499
      WBInteraction000040506
      WBInteraction000040507
      WBInteraction000040816
      WBInteraction000041571
      WBInteraction000041572
      WBInteraction000041573
      WBInteraction000042630
      WBInteraction000043703
      WBInteraction000044146
      WBInteraction000047785
      WBInteraction000048864
      WBInteraction000049589
      WBInteraction000050135
      WBInteraction000050136
      WBInteraction000050137
      WBInteraction000050138
      WBInteraction000101451
      WBInteraction000103015
      WBInteraction000103025
      WBInteraction000103632
      WBInteraction000103751
      WBInteraction000103780
      WBInteraction000105154
      WBInteraction000106175
      WBInteraction000108919
      WBInteraction000110463
      WBInteraction000111084
      WBInteraction000111427
      WBInteraction000116128
      WBInteraction000123968
      WBInteraction000124537
      WBInteraction000125363
      WBInteraction000125401
      WBInteraction000125404
      WBInteraction000125411
      WBInteraction000125429
      WBInteraction000125433
      WBInteraction000125442
      WBInteraction000125443
      WBInteraction000125444
      WBInteraction000125464
      WBInteraction000125595
      WBInteraction000127639
      WBInteraction000127865
      WBInteraction000127909
      WBInteraction000128292
      WBInteraction000128383
      WBInteraction000128416
      WBInteraction000128541
      WBInteraction000128607
      WBInteraction000128670
      WBInteraction000128794
      WBInteraction000128915
      WBInteraction000128948
      WBInteraction000130198
      WBInteraction000130315
      WBInteraction000130316
      WBInteraction000130317
      WBInteraction000130318
      WBInteraction000130319
      WBInteraction000130320
      WBInteraction000130321
      WBInteraction000130322
      WBInteraction000130323
      WBInteraction000130324
      WBInteraction000130325
      WBInteraction000130326
      WBInteraction000130327
      WBInteraction000130328
      WBInteraction000130329
      WBInteraction000130330
      WBInteraction000130659
      WBInteraction000130733
      WBInteraction000130885
      WBInteraction000130971
      WBInteraction000131047
      WBInteraction000131244
      WBInteraction000131335
      WBInteraction000131385
      WBInteraction000131423
      WBInteraction000131495
      WBInteraction000131560
      WBInteraction000131617
      WBInteraction000131642
      WBInteraction000131857
      WBInteraction000131969
      WBInteraction000132045
      WBInteraction000132108
      WBInteraction000132150
      WBInteraction000132212
      WBInteraction000132287
      WBInteraction000132345
      WBInteraction000132418
      WBInteraction000132472
      WBInteraction000132543
      WBInteraction000132689
      WBInteraction000132803
      WBInteraction000132851
      WBInteraction000138770
      WBInteraction000142237
      WBInteraction000146752
      WBInteraction000157364
      WBInteraction000158727
      WBInteraction000158737
      WBInteraction000158792
      WBInteraction000158798
      WBInteraction000158822
      WBInteraction000158865
      WBInteraction000158866
      WBInteraction000159098
      WBInteraction000159165
      WBInteraction000159210
      WBInteraction000159237
      WBInteraction000159376
      WBInteraction000159490
      WBInteraction000159502
      WBInteraction000167547
      WBInteraction000170035
      WBInteraction000171148
      WBInteraction000174243
      WBInteraction000189701
      WBInteraction000194838
      WBInteraction000201488
      WBInteraction000204694
      WBInteraction000211968
      WBInteraction000217424
      WBInteraction000224544
      WBInteraction000226240
      WBInteraction000236647
      WBInteraction000243785
      WBInteraction000244218
      WBInteraction000249698
      WBInteraction000266413
      WBInteraction000270994
      WBInteraction000301173
      WBInteraction000303523
      WBInteraction000306172
      WBInteraction000307521
      WBInteraction000312306
      WBInteraction000318062
      WBInteraction000324296
      WBInteraction000324863
      WBInteraction000334363
      WBInteraction000347125
      WBInteraction000350219
      WBInteraction000357876
      WBInteraction000357987
      WBInteraction000364261
      WBInteraction000364797
      WBInteraction000366622
      WBInteraction000367440
      WBInteraction000370353
      WBInteraction000372908
      WBInteraction000377244
      WBInteraction000378763
      WBInteraction000386957
      WBInteraction000388695
      WBInteraction000394818
      WBInteraction000400561
      WBInteraction000403379
      WBInteraction000408361
      WBInteraction000408818
      WBInteraction000425194
      WBInteraction000443300
      WBInteraction000448112
      WBInteraction000455125
      WBInteraction000458961
      WBInteraction000463686
      WBInteraction000465529
      WBInteraction000468105
      WBInteraction000502489
      WBInteraction000540242
      WBInteraction000542052
      WBInteraction000542065
      WBInteraction000543400
      WBInteraction000547040
      WBInteraction000551318
      WBInteraction000555550
      WBInteraction000558474
      WBInteraction000562014
      WBInteraction000565742
      WBInteraction000566837
      WBInteraction000567521
      WBInteraction000568143
      WBInteraction000575025
      WBInteraction000577779
      WBInteraction000579788
  Map_info: Map: II Position: -0.218968 Error: 0.002781
    Positive: Positive_clone: T28D9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005457
    WBPaper00027057
    WBPaper00038491
    WBPaper00046572
    WBPaper00049828
    WBPaper00055090
    WBPaper00063976
    WBPaper00064663
  Remark: Locus was previously incorrectly associated with C52E4.3. [krb 030219]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene