WormBase Tree Display for Gene: WBGene00004889
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| WBGene00004889 | SMap | S_parent | Sequence | Y54E5B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | smp-1 | Person_evidence | WBPerson893 | |||||
| Sequence_name | Y54E5B.1 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | cesema | Accession_evidence | EMBL | U15667 | |||||
| CELE_Y54E5B.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | smp-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | smp | ||||||||
| Allele (144) | |||||||||
| Strain | WBStrain00029151 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (102) | |||||||||
| Paralog | WBGene00003111 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00004890 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | smp-1 encodes a semaphorin; smp-1 activity is required for vulval morphogenesis, specifically for the movement of homologous pairs of vulval cells towards the vulval midline prior to cell fusion; smp-1 expression in vulval cells is regulated by the VAB-23 zinc-finger domain protein which binds smp-1 regulatory sequence in vivo. | Paper_evidence | WBPaper00040292 | |||||
| WBPaper00025151 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Oct 2011 00:00:00 | ||||||||
| Automated_description | Enables semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hermaphrodite distal tip cell; non-striated muscle; ray; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia; progressive myoclonus epilepsy; and rheumatoid arthritis. Is an ortholog of several human genes including SEMA3B (semaphorin 3B); SEMA3C (semaphorin 3C); and SEMA6C (semaphorin 6C). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:7148 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10725) | ||||
| DOID:0090080 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10723) | ||||||
| DOID:891 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10739) | ||||||
| Molecular_info | Corresponding_CDS | Y54E5B.1a | |||||||
| Y54E5B.1b | |||||||||
| Y54E5B.1c | |||||||||
| Corresponding_transcript | Y54E5B.1a.1 | ||||||||
| Y54E5B.1b.1 | |||||||||
| Y54E5B.1b.2 | |||||||||
| Y54E5B.1b.3 | |||||||||
| Y54E5B.1b.4 | |||||||||
| Y54E5B.1c.1 | |||||||||
| Other_sequence (24) | |||||||||
| Associated_feature (24) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00065917 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00022980 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022981 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116872 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057388 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004745 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091930 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1885 | ||||||||
| Expr3276 | |||||||||
| Expr9188 | |||||||||
| Expr1026364 | |||||||||
| Expr1032428 | |||||||||
| Expr1160822 | |||||||||
| Expr2015922 | |||||||||
| Expr2034155 | |||||||||
| Drives_construct (15) | |||||||||
| Construct_product (20) | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (129) | |||||||||
| Interaction (45) | |||||||||
| Anatomy_function | WBbtf0686 | ||||||||
| WBbtf0687 | |||||||||
| WBbtf0688 | |||||||||
| WBbtf0689 | |||||||||
| WBbtf0690 | |||||||||
| WBbtf0691 | |||||||||
| WBbtf1066 | |||||||||
| Map_info | Map | I | Position | 27.3982 | Error | 0.247471 | |||
| Positive | Positive_clone | Y54E5B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4669 | |||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
