WormBase Tree Display for Gene: WBGene00004873

WBGene00004873 Evidence: Paper_evidence: WBPaper00005919
  SMap: S_parent: Sequence: Y47D3A
  Identity: Version: 1
    Name: CGC_name: smc-3 Person_evidence: WBPerson203
      Sequence_name: Y47D3A.26
      Molecular_name: Y47D3A.26a
        Y47D3A.26a.1
        CE41472
        Y47D3A.26c
        CE47674
        Y47D3A.26c.1
      Other_name: Y47D3A Paper_evidence: WBPaper00027033
        CELE_Y47D3A.26 Accession_evidence: NDB BX284603
      Public_name: smc-3
    DB_info: Database: AceView gene 3M395
        WormQTL gene WBGene00004873
        WormFlux gene WBGene00004873
        NDB locus_tag CELE_Y47D3A.26
        Panther gene CAEEL|WormBase=WBGene00004873|UniProtKB=B2FDA8
          family PTHR43977
        NCBI gene 176559
        RefSeq protein NM_001268190.3
            NM_001268189.4
        SwissProt UniProtAcc B2FDA8
        UniProt_GCRP UniProtAcc B2FDA8
        OMIM gene 606062
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: smc
    Allele (301)
    Strain: WBStrain00036443
      WBStrain00007808
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (40)
    Paralog: WBGene00001086 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001860 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003367 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004874 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00010306 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012198 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016172 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019087 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00044079 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable cohesin loader activity and double-stranded DNA binding activity. Predicted to be involved in mitotic sister chromatid cohesion. Part of chromatin and cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Is an ortholog of human SMC3 (structural maintenance of chromosomes 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080507 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2468)
      DOID:1059 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2468)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2468)
  Molecular_info: Corresponding_CDS: Y47D3A.26a
      Y47D3A.26c
    Corresponding_CDS_history: Y47D3A.26:wp130
      Y47D3A.26:wp179
      Y47D3A.26b:wp273
    Corresponding_transcript: Y47D3A.26a.1
      Y47D3A.26c.1
    Other_sequence (65)
    Associated_feature (11)
  Experimental_info: RNAi_result (22)
    Expr_pattern: Expr1013320
      Expr1032414
      Expr1160210
      Expr2015898
      Expr2034131
    Antibody: WBAntibody00000638
      WBAntibody00002074
      WBAntibody00002279
      WBAntibody00002399
    Microarray_results (24)
    Expression_cluster (148)
    Interaction (145)
    WBProcess: WBbiopr:00000099
  Map_info: Map: III Position: 8.3815 Error: 0.026044
    Positive: Positive_clone: Y47D3A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (17)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene