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WormBase Tree Display for Gene: WBGene00004391

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Name Class

WBGene00004391SMapS_parentSequenceT23G5
IdentityVersion1
NameCGC_namernr-1Person_evidenceWBPerson732
Sequence_nameT23G5.1
Molecular_nameT23G5.1
T23G5.1.1
CE00331
T23G5.1.2
Other_nameCELE_T23G5.1Accession_evidenceNDBBX284603
Public_namernr-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrnr
Allele (36)
StrainWBStrain00002226
WBStrain00007244
WBStrain00007246
WBStrain00001716
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (47)
Structured_descriptionConcise_descriptionrnr-1 encodes the large subunit of ribonucleotide reductase; by homology, RNR-1 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-1 is an essential gene whose activity is required for reproduction and embryonic development.Curator_confirmedWBPerson1843
Date_last_updated02 Aug 2007 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Expressed in head; somatic gonad precursor; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human RRM1 (ribonucleotide reductase catalytic subunit M1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
DOID:12558Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
Molecular_infoCorresponding_CDST23G5.1
Corresponding_transcriptT23G5.1.1
T23G5.1.2
Other_sequence (105)
Associated_feature (15)
Experimental_infoRNAi_result (25)
Expr_pattern (11)
Drives_constructWBCnstr00000444
WBCnstr00000446
WBCnstr00000447
WBCnstr00000929
WBCnstr00002540
WBCnstr00004370
WBCnstr00007949
WBCnstr00008139
WBCnstr00035516
Construct_productWBCnstr00035516
AntibodyWBAntibody00001448
Microarray_results (21)
Expression_cluster (236)
Interaction (152)
Map_infoMapIIIPosition0.326335Error0.008197
PositivePositive_cloneT23G5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkSequence connection from [Ambros V]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene