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WormBase Tree Display for Gene: WBGene00004391

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Name Class

WBGene00004391SMapS_parentSequenceT23G5
IdentityVersion1
NameCGC_namernr-1Person_evidenceWBPerson732
Sequence_nameT23G5.1
Molecular_nameT23G5.1
T23G5.1.1
CE00331
T23G5.1.2
Other_nameCELE_T23G5.1Accession_evidenceNDBBX284603
Public_namernr-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrnr
Allele (36)
StrainWBStrain00002226
WBStrain00007244
WBStrain00007246
WBStrain00001716
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (47)
Structured_descriptionConcise_descriptionrnr-1 encodes the large subunit of ribonucleotide reductase; by homology, RNR-1 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-1 is an essential gene whose activity is required for reproduction and embryonic development.Curator_confirmedWBPerson1843
Date_last_updated02 Aug 2007 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Expressed in head; somatic gonad precursor; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human RRM1 (ribonucleotide reductase catalytic subunit M1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
DOID:12558Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
Molecular_infoCorresponding_CDST23G5.1
Corresponding_transcriptT23G5.1.1
T23G5.1.2
Other_sequenceFC550799.1
CR04526
ACC34623_1
SS01719
AM157811.1
SSC02582_1
EX535453.1
Acan_isotig00966
MIC04836_1
MHC02812_1
EX565468.1
FC817421.1
ACC05889_1
SR04881
Acan_isotig00965
FK809668.1
AE03384
EY469211.1
EX560349.1
PPC12633_1
FC819818.1
CGC00101_1
PSC00556_1
Tcol_isotig01417
Tcir_isotig00503
FC810668.1
Tcol_isotig01419
Tcol_isotig01415
EX552489.1
RS06926
EY464259.1
FC550922.1
Tcol_isotig01416
SR04619
MHC03141_1
SS02068
Tcol_isotig01418
MH06965
EY472815.1
TIC00061_1
MI06512
FK809956.1
GW406080.1
ODC00073_1
JI476335.1
EX535866.1
EX560041.1
CRC03709_1
PPC05147_1
SRC01799_1
Hbac_isotig01243
EY466443.1
FC553819.1
FC542143.1
FC811840.1
FC547447.1
BQ804054.1
HBC10050_1
OOC03861_1
EX561933.1
SSC00047_1
FC820158.1
FC539738.1
EG025758.1
EY459810.1
EY460483.1
FC813899.1
HG07872
AM157823.1
SS00752
MH06803
FC816105.1
PPC10228_1
FK808632.1
EY469300.1
BXC04407_1
Tcir_isotig00504
EX559709.1
Acan_isotig00963
HG00258
CRC12168_1
EX554094.1
MIC05481_1
CR02224
CJC01033_1
AYC01734_1
AJ616419.1
CGC00827_1
SRC09090_1
EW744046.1
CRC00108_1
MH00935
EY465819.1
HGC04333_1
Dviv_isotig17373
RSC03547_1
SSC03855_1
EW743439.1
EX564400.1
EY473155.1
Acan_isotig00964
JI167846.1
CR05959
SRC06081_1
CR08803
Associated_feature (15)
Experimental_infoRNAi_result (25)
Expr_pattern (11)
Drives_constructWBCnstr00000444
WBCnstr00000446
WBCnstr00000447
WBCnstr00000929
WBCnstr00002540
WBCnstr00004370
WBCnstr00007949
WBCnstr00008139
WBCnstr00035516
Construct_productWBCnstr00035516
AntibodyWBAntibody00001448
Microarray_results (21)
Expression_cluster (236)
Interaction (152)
Map_infoMapIIIPosition0.326335Error0.008197
PositivePositive_cloneT23G5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkSequence connection from [Ambros V]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene