WormBase Tree Display for Gene: WBGene00004391
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WBGene00004391 | SMap | S_parent | Sequence | T23G5 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rnr | ||||||
Allele (36) | |||||||
Strain | WBStrain00002226 | ||||||
WBStrain00007244 | |||||||
WBStrain00007246 | |||||||
WBStrain00001716 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (17) | |||||||
Ortholog (47) | |||||||
Structured_description | Concise_description | rnr-1 encodes the large subunit of ribonucleotide reductase; by homology, RNR-1 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-1 is an essential gene whose activity is required for reproduction and embryonic development. | Curator_confirmed | WBPerson1843 | |||
Date_last_updated | 02 Aug 2007 00:00:00 | ||||||
Automated_description | Predicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Expressed in head; somatic gonad precursor; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human RRM1 (ribonucleotide reductase catalytic subunit M1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10451) | ||
DOID:12558 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10451) | ||||
Molecular_info | Corresponding_CDS | T23G5.1 | |||||
Corresponding_transcript | T23G5.1.1 | ||||||
T23G5.1.2 | |||||||
Other_sequence (105) | |||||||
Associated_feature (15) | |||||||
Experimental_info | RNAi_result (25) | ||||||
Expr_pattern (11) | |||||||
Drives_construct | WBCnstr00000444 | ||||||
WBCnstr00000446 | |||||||
WBCnstr00000447 | |||||||
WBCnstr00000929 | |||||||
WBCnstr00002540 | |||||||
WBCnstr00004370 | |||||||
WBCnstr00007949 | |||||||
WBCnstr00008139 | |||||||
WBCnstr00035516 | |||||||
Construct_product | WBCnstr00035516 | ||||||
Antibody | WBAntibody00001448 | ||||||
Microarray_results (21) | |||||||
Expression_cluster (236) | |||||||
Interaction (152) | |||||||
Map_info | Map | III | Position | 0.326335 | Error | 0.008197 | |
Positive | Positive_clone | T23G5 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Pseudo_map_position | |||||||
Reference (14) | |||||||
Remark | Sequence connection from [Ambros V] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |