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WormBase Tree Display for Gene: WBGene00004391

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Name Class

WBGene00004391SMapS_parentSequenceT23G5
IdentityVersion1
NameCGC_namernr-1Person_evidenceWBPerson732
Sequence_nameT23G5.1
Molecular_nameT23G5.1
T23G5.1.1
CE00331
T23G5.1.2
Other_nameCELE_T23G5.1Accession_evidenceNDBBX284603
Public_namernr-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrnr
AlleleWBVar01409097
WBVar00404924
WBVar00404925
WBVar00404926
WBVar01500260
WBVar01447440
WBVar01723120
WBVar00233990
WBVar00849251
WBVar00849252
WBVar00849253
WBVar00849254
WBVar00849255
WBVar00849256
WBVar00849257
WBVar00849258
WBVar00849259
WBVar00849260
WBVar00849261
WBVar00849262
WBVar00849263
WBVar00849264
WBVar00849265
WBVar01499774
WBVar00849266
WBVar00849267
WBVar02132489
WBVar00251811
WBVar01629259
WBVar01629260
WBVar01896377
WBVar00070453
WBVar01939503
WBVar00307938
WBVar00404922
WBVar00404923
StrainWBStrain00002226
WBStrain00007244
WBStrain00007246
WBStrain00001716
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (47)
Structured_descriptionConcise_descriptionrnr-1 encodes the large subunit of ribonucleotide reductase; by homology, RNR-1 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-1 is an essential gene whose activity is required for reproduction and embryonic development.Curator_confirmedWBPerson1843
Date_last_updated02 Aug 2007 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Expressed in head; somatic gonad precursor; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human RRM1 (ribonucleotide reductase catalytic subunit M1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
DOID:12558Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10451)
Molecular_infoCorresponding_CDST23G5.1
Corresponding_transcriptT23G5.1.1
T23G5.1.2
Other_sequence (105)
Associated_feature (15)
Experimental_infoRNAi_result (25)
Expr_pattern (11)
Drives_constructWBCnstr00000444
WBCnstr00000446
WBCnstr00000447
WBCnstr00000929
WBCnstr00002540
WBCnstr00004370
WBCnstr00007949
WBCnstr00008139
WBCnstr00035516
Construct_productWBCnstr00035516
AntibodyWBAntibody00001448
Microarray_results (21)
Expression_cluster (236)
Interaction (152)
Map_infoMapIIIPosition0.326335Error0.008197
PositivePositive_cloneT23G5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (14)
RemarkSequence connection from [Ambros V]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene