WormBase Tree Display for Gene: WBGene00004053
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| WBGene00004053 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tank-1 | Person_evidence | WBPerson236 | |||||
| Sequence_name | ZK1005.1 | ||||||||
| Molecular_name | ZK1005.1a | ||||||||
| ZK1005.1a.1 | |||||||||
| CE24712 | |||||||||
| ZK1005.1b | |||||||||
| CE33259 | |||||||||
| ZK1005.1b.1 | |||||||||
| Other_name | pme-5 | ||||||||
| CELE_ZK1005.1 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | tank-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 18 Nov 2014 11:51:19 | WBPerson2970 | Name_change | CGC_name | tank-1 | ||||
| Other_name | pme-5 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tank | ||||||||
| Allele (183) | |||||||||
| Strain | WBStrain00031422 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (29) | |||||||||
| Paralog | WBGene00004049 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00004050 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | tank-1 (formerly known as pme-5) encodes a protein containing N-terminal ankyrin repeats and C-terminal poly (ADP-ribose) polymerase (PARP) regulatory and catalytic domains that is orthologous to human tankyrase 1 (TNKS; OMIM:603303) and tankyrase 2 (TNKS2; OMIM: 607128), but structurally more similar to the ADPRT-3 tankyrase of Dictyostelium discoideum; TANK-1 also contains a lysine-rich region, a WGR domain, which may mediate DNA interaction, and a coil-coiled region; X-ray-induced apoptosis of germ cells is slightly increased in tank-1(RNAi) animals; DNA damage via ionizing radiation induces tank-1 expression, and this induction absolutely requires HUS-1; TANK-1 is ubiquitously expressed throughout the life cycle, including in the germ line, and localizes to the nucleus. | Paper_evidence | WBPaper00005600 | |||||
| WBPaper00006357 | |||||||||
| WBPaper00032454 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Nov 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable NAD+ ADP-ribosyltransferase activity and NAD+-protein ADP-ribosyltransferase activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of programmed cell death; and response to gamma radiation. Located in nucleus. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK1005.1a | |||||||
| ZK1005.1b | |||||||||
| Corresponding_transcript | ZK1005.1a.1 | ||||||||
| ZK1005.1b.1 | |||||||||
| Other_sequence | Oden_isotig21192 | ||||||||
| JI163989.1 | |||||||||
| DN190409.1 | |||||||||
| Hbac_isotig06157 | |||||||||
| CRC03985_1 | |||||||||
| CJC00359_1 | |||||||||
| AAC00581_1 | |||||||||
| CR12145 | |||||||||
| CBC08961_1 | |||||||||
| Dviv_isotig23950 | |||||||||
| Associated_feature | WBsf652468 | ||||||||
| WBsf999295 | |||||||||
| WBsf999296 | |||||||||
| WBsf1019159 | |||||||||
| WBsf233325 | |||||||||
| WBsf233326 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00098031 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00059031 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061225 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098001 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021767 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021435 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8972 | ||||||||
| Expr11816 | |||||||||
| Expr1028040 | |||||||||
| Expr1031952 | |||||||||
| Expr1162461 | |||||||||
| Expr2017296 | |||||||||
| Expr2035431 | |||||||||
| Drives_construct | WBCnstr00037943 | ||||||||
| Construct_product | WBCnstr00037943 | ||||||||
| Antibody | WBAntibody00001710 | ||||||||
| WBAntibody00001711 | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (193) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | V | Position | -19.844 | Error | 0.004452 | |||
| Positive | Positive_clone | ZK1005 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4593 | |||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Sequence connection via email from [Desnoyers S], [krb 020729] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
