WormBase Tree Display for Gene: WBGene00003877
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| WBGene00003877 | SMap | S_parent | Sequence | K04E7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pept-1 | Person_evidence | WBPerson2603 | |||||
| WBPerson861 | |||||||||
| Sequence_name | K04E7.2 | ||||||||
| Molecular_name | K04E7.2 | ||||||||
| K04E7.2.1 | |||||||||
| CE25039 | |||||||||
| Other_name | pep-2 | ||||||||
| opt-2 | |||||||||
| CELE_K04E7.2 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | pept-1 | ||||||||
| DB_info | Database | AceView | gene | XH79 | |||||
| WormQTL | gene | WBGene00003877 | |||||||
| WormFlux | gene | WBGene00003877 | |||||||
| NDB | locus_tag | CELE_K04E7.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003877|UniProtKB=Q21219 | |||||||
| family | PTHR11654 | ||||||||
| NCBI | gene | 180919 | |||||||
| RefSeq | protein | NM_076686.7 | |||||||
| SwissProt | UniProtAcc | Q21219 | |||||||
| UniProt_GCRP | UniProtAcc | Q21219 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Apr 2009 13:55:02 | WBPerson9133 | Name_change | CGC_name | pept-1 | ||||
| Other_name | opt-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pept | ||||||||
| Allele (85) | |||||||||
| Possibly_affected_by | WBVar02157263 | ||||||||
| Strain | WBStrain00036075 | ||||||||
| WBStrain00003894 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (46) | |||||||||
| Ortholog (46) | |||||||||
| Paralog | WBGene00003876 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003878 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane. | Paper_evidence | WBPaper00006186 | |||||
| WBPaper00024423 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 05 Nov 2009 00:00:00 | ||||||||
| Automated_description | Enables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00034742 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 15 Sep 2021 00:00:00 | ||||||||
| Models_disease_asserted | WBDOannot00000178 | ||||||||
| Molecular_info | Corresponding_CDS | K04E7.2 | |||||||
| Corresponding_transcript | K04E7.2.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf662881 | ||||||||
| WBsf978975 | |||||||||
| WBsf1005576 | |||||||||
| WBsf1023101 | |||||||||
| WBsf235837 | |||||||||
| Experimental_info | RNAi_result (49) | ||||||||
| Expr_pattern | Expr1421 | ||||||||
| Expr8048 | |||||||||
| Expr8049 | |||||||||
| Expr10732 | |||||||||
| Expr1026620 | |||||||||
| Expr1031825 | |||||||||
| Expr1153607 | |||||||||
| Expr2014823 | |||||||||
| Expr2033057 | |||||||||
| Marker28 | |||||||||
| Drives_construct (23) | |||||||||
| Construct_product | WBCnstr00004990 | ||||||||
| WBCnstr00009194 | |||||||||
| WBCnstr00013078 | |||||||||
| WBCnstr00014892 | |||||||||
| WBCnstr00016252 | |||||||||
| WBCnstr00018325 | |||||||||
| WBCnstr00037949 | |||||||||
| Regulate_expr_cluster | WBPaper00045460:Co-expression_Cluster_1 | ||||||||
| WBPaper00045460:Co-expression_Cluster_2 | |||||||||
| WBPaper00045460:Co-expression_Cluster_3 | |||||||||
| WBPaper00045460:pept-1(lg601)_downregulated | |||||||||
| WBPaper00045460:pept-1(lg601)_upregulated | |||||||||
| Antibody | WBAntibody00002276 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (236) | |||||||||
| Interaction (114) | |||||||||
| Map_info | Map | X | Position | -2.89742 | Error | 0.002559 | |||
| Positive | Positive_clone | K04E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (57) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
