WormBase Tree Display for Gene: WBGene00003877
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WBGene00003877 | SMap | S_parent | Sequence | K04E7 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | pept | ||||||
Allele (85) | |||||||
Possibly_affected_by | WBVar02157263 | ||||||
Strain | WBStrain00036075 | ||||||
WBStrain00003894 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (46) | |||||||
Ortholog (46) | |||||||
Paralog | WBGene00003876 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00003878 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | pept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane. | Paper_evidence | WBPaper00006186 | |||
WBPaper00024423 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 05 Nov 2009 00:00:00 | ||||||
Automated_description | Enables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00034742 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 15 Sep 2021 00:00:00 | ||||||
Models_disease_asserted | WBDOannot00000178 | ||||||
Molecular_info | Corresponding_CDS | K04E7.2 | |||||
Corresponding_transcript | K04E7.2.1 | ||||||
Other_sequence (23) | |||||||
Associated_feature | WBsf662881 | ||||||
WBsf978975 | |||||||
WBsf1005576 | |||||||
WBsf1023101 | |||||||
WBsf235837 | |||||||
Experimental_info | RNAi_result (49) | ||||||
Expr_pattern | Expr1421 | ||||||
Expr8048 | |||||||
Expr8049 | |||||||
Expr10732 | |||||||
Expr1026620 | |||||||
Expr1031825 | |||||||
Expr1153607 | |||||||
Expr2014823 | |||||||
Expr2033057 | |||||||
Marker28 | |||||||
Drives_construct (23) | |||||||
Construct_product | WBCnstr00004990 | ||||||
WBCnstr00009194 | |||||||
WBCnstr00013078 | |||||||
WBCnstr00014892 | |||||||
WBCnstr00016252 | |||||||
WBCnstr00018325 | |||||||
WBCnstr00037949 | |||||||
Regulate_expr_cluster | WBPaper00045460:Co-expression_Cluster_1 | ||||||
WBPaper00045460:Co-expression_Cluster_2 | |||||||
WBPaper00045460:Co-expression_Cluster_3 | |||||||
WBPaper00045460:pept-1(lg601)_downregulated | |||||||
WBPaper00045460:pept-1(lg601)_upregulated | |||||||
Antibody | WBAntibody00002276 | ||||||
Microarray_results (20) | |||||||
Expression_cluster (236) | |||||||
Interaction (114) | |||||||
Map_info | Map | X | Position | -2.89742 | Error | 0.002559 | |
Positive | Positive_clone | K04E7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (57) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |