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WormBase Tree Display for Gene: WBGene00003851

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Name Class

WBGene00003851SMapS_parentSequenceY102E9
IdentityVersion1
NameCGC_nameodr-4Person_evidenceWBPerson42
Sequence_nameY102E9.1
Molecular_name (12)
Other_nameCELE_Y102E9.1Accession_evidenceNDBBX284603
Public_nameodr-4
DB_infoDatabaseAceViewgene3H823
WormQTLgeneWBGene00003851
WormFluxgeneWBGene00003851
NDBlocus_tagCELE_Y102E9.1
PanthergeneCAEEL|WormBase=WBGene00003851|UniProtKB=Q8I7F8
familyPTHR33966
NCBIgene175950
RefSeqproteinNM_001027644.9
NM_001382900.2
NM_001392129.1
SwissProtUniProtAccQ8I7F8
TREEFAMTREEFAM_IDTF320359
UniProt_GCRPUniProtAccQ8I7F8
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classodr
Allele (48)
Legacy_information[Bargmann CI] defective chemotaxis to volatile odorants
[C.elegansII] n2144 : defective chemotaxis to some volatile odoratants. n2144/Df similar. NA1. [Bargmann et al. 1993]
[Dwyer ND] n2144 defective in odorant response to benzaldehyde, diacetyl, normal response to isoamyl alcohol, pyrazine. Fails to localize ODR-10 to cilia of AWA neurons. n2144 rescued by subclone including Y102E9.1, encoding 445 aa protein. n2144 is M372L plus splice acceptor change.
StrainWBStrain00027204
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (31)
Structured_descriptionConcise_descriptionodr-4 encodes a novel type II membrane protein; ODR-4 is required for localization of a subset of G protein-coupled receptors (GPCRs)s, including ODR-10, to the cilia of olfactory neurons; ODR-4 affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; ODR-4 physically interacts with ODR-8 to form a complex at the endoplasmic reticulum membrane, and physically interacts wtih ODR-10, as well; ODR-4 is expressed in twelve pairs of chemosensory neurons: the ten amphid neurons and two phasmid neurons; odr-4 expression overlaps that of odr-8.Paper_evidenceWBPaper00003063
WBPaper00005511
WBPaper00044965
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated02 May 2014 00:00:00
Automated_descriptionInvolved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY102E9.1a
Y102E9.1b
Y102E9.1c
Corresponding_transcriptY102E9.1a.1
Y102E9.1a.2
Y102E9.1a.3
Y102E9.1a.4
Y102E9.1b.1
Y102E9.1c.1
Other_sequence (31)
Associated_featureWBsf042313
WBsf645280
WBsf645281
WBsf992840
WBsf1015145
WBsf225148
Experimental_infoRNAi_resultWBRNAi00005178Inferred_automaticallyRNAi_primary
WBRNAi00055160Inferred_automaticallyRNAi_primary
WBRNAi00005789Inferred_automaticallyRNAi_primary
WBRNAi00055159Inferred_automaticallyRNAi_primary
WBRNAi00005790Inferred_automaticallyRNAi_primary
WBRNAi00055161Inferred_automaticallyRNAi_primary
WBRNAi00055157Inferred_automaticallyRNAi_primary
WBRNAi00019822Inferred_automaticallyRNAi_primary
WBRNAi00005720Inferred_automaticallyRNAi_primary
WBRNAi00027800Inferred_automaticallyRNAi_primary
Expr_patternExpr1432
Expr10139
Expr11650
Expr13173
Expr1011843
Expr1031817
Expr1158687
Expr2014610
Expr2032843
Drives_constructWBCnstr00010274
WBCnstr00019303
WBCnstr00021696
WBCnstr00035829
WBCnstr00041883
Construct_productWBCnstr00010274
WBCnstr00019303
WBCnstr00035829
Microarray_results (36)
Expression_cluster (103)
Interaction (72)
Anatomy_functionWBbtf0086
WBbtf1049
Map_infoMapIIIPosition-0.951383Error0.006326
Well_ordered
PositivePositive_cloneC28A6
Y102E9Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeNegative_cloneF37A4Author_evidenceDwyer ND
K07E12Author_evidenceDwyer ND
Mapping_dataMulti_point2055
2056
2057
2058
4976
5453
Pos_neg_data5983
Reference (40)
RemarkData extracted from Dwyer et al. (1998)
MethodGene