WBGene00003851 | SMap | S_parent | Sequence | Y102E9 |
| Identity | Version | 1 |
| | Name | CGC_name | odr-4 | Person_evidence | WBPerson42 |
| | | Sequence_name | Y102E9.1 |
| | | Molecular_name (12) |
| | | Other_name | CELE_Y102E9.1 | Accession_evidence | NDB | BX284603 |
| | | Public_name | odr-4 |
| | DB_info | Database | AceView | gene | 3H823 |
| | | | WormQTL | gene | WBGene00003851 |
| | | | WormFlux | gene | WBGene00003851 |
| | | | NDB | locus_tag | CELE_Y102E9.1 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00003851|UniProtKB=Q8I7F8 |
| | | | | family | PTHR33966 |
| | | | NCBI | gene | 175950 |
| | | | RefSeq | protein | NM_001027644.9 |
| | | | | | NM_001382900.2 |
| | | | | | NM_001392129.1 |
| | | | SwissProt | UniProtAcc | Q8I7F8 |
| | | | TREEFAM | TREEFAM_ID | TF320359 |
| | | | UniProt_GCRP | UniProtAcc | Q8I7F8 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | odr |
| | Allele (48) |
| | Legacy_information | [Bargmann CI] defective chemotaxis to volatile odorants |
| | | [C.elegansII] n2144 : defective chemotaxis to some volatile odoratants. n2144/Df similar. NA1. [Bargmann et al. 1993] |
| | | [Dwyer ND] n2144 defective in odorant response to benzaldehyde, diacetyl, normal response to isoamyl alcohol, pyrazine. Fails to localize ODR-10 to cilia of AWA neurons. n2144 rescued by subclone including Y102E9.1, encoding 445 aa protein. n2144 is M372L plus splice acceptor change. |
| | Strain | WBStrain00027204 |
| | RNASeq_FPKM (74) |
| | GO_annotation (22) |
| | Ortholog (31) |
| | Structured_description | Concise_description | odr-4 encodes a novel type II membrane protein; ODR-4 is required for localization of a subset of G protein-coupled receptors (GPCRs)s, including ODR-10, to the cilia of olfactory neurons; ODR-4 affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; ODR-4 physically interacts with ODR-8 to form a complex at the endoplasmic reticulum membrane, and physically interacts wtih ODR-10, as well; ODR-4 is expressed in twelve pairs of chemosensory neurons: the ten amphid neurons and two phasmid neurons; odr-4 expression overlaps that of odr-8. | Paper_evidence | WBPaper00003063 |
| | | | | | WBPaper00005511 |
| | | | | | WBPaper00044965 |
| | | | | Curator_confirmed | WBPerson48 |
| | | | | | WBPerson1843 |
| | | | | Date_last_updated | 02 May 2014 00:00:00 |
| | | Automated_description | Involved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | Y102E9.1a |
| | | Y102E9.1b |
| | | Y102E9.1c |
| | Corresponding_transcript | Y102E9.1a.1 |
| | | Y102E9.1a.2 |
| | | Y102E9.1a.3 |
| | | Y102E9.1a.4 |
| | | Y102E9.1b.1 |
| | | Y102E9.1c.1 |
| | Other_sequence (31) |
| | Associated_feature | WBsf042313 |
| | | WBsf645280 |
| | | WBsf645281 |
| | | WBsf992840 |
| | | WBsf1015145 |
| | | WBsf225148 |
| Experimental_info | RNAi_result | WBRNAi00005178 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00055160 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005789 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00055159 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005790 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00055161 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00055157 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00019822 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005720 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00027800 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1432 |
| | | Expr10139 |
| | | Expr11650 |
| | | Expr13173 |
| | | Expr1011843 |
| | | Expr1031817 |
| | | Expr1158687 |
| | | Expr2014610 |
| | | Expr2032843 |
| | Drives_construct | WBCnstr00010274 |
| | | WBCnstr00019303 |
| | | WBCnstr00021696 |
| | | WBCnstr00035829 |
| | | WBCnstr00041883 |
| | Construct_product | WBCnstr00010274 |
| | | WBCnstr00019303 |
| | | WBCnstr00035829 |
| | Microarray_results (36) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032031:DConiospora_downregulated_OligoArray_24h |
| | | WBPaper00033065:cyc-1(RNAi)_downregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049498:npr-1(ur89)_regulated_3 |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated |
| | | WBPaper00050488:20C_vs_25C_regulated_N2_adult |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053289:DREAM-target |
| | | WBPaper00053388:dauer_regulated_Cluster3 |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00058942:henn-1(pk2295)_downregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061340:ADF |
| | | WBPaper00061340:ADF_AWB |
| | | WBPaper00061340:ADL |
| | | WBPaper00061340:ASG |
| | | WBPaper00061340:ASG_AWA |
| | | WBPaper00061340:ASH |
| | | WBPaper00061340:ASI |
| | | WBPaper00061340:ASJ |
| | | WBPaper00061340:ASK |
| | | WBPaper00061340:AWA |
| | | WBPaper00061340:AWB |
| | | WBPaper00061340:AWC |
| | | WBPaper00061527:C30H6.7-Y106G6H.5_2231 |
| | | WBPaper00061651:ADF_enriched |
| | | WBPaper00061651:ADL_enriched |
| | | WBPaper00061651:ASH_enriched |
| | | WBPaper00061651:ASI_enriched |
| | | WBPaper00061651:ASJ_enriched |
| | | WBPaper00061651:ASK_enriched |
| | | WBPaper00061651:AWB_enriched |
| | | WBPaper00061651:PHA_enriched |
| | | WBPaper00061651:PHB_enriched |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064494:postdauer_downregulated_AWA |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00064789:Day6_vs_Day1_upregulated_neuron |
| | | WBPaper00064789:Day9_vs_Day1_upregulated_neuron |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00066085:hda-3(ok1991)_downregulated |
| | | WBPaper00066085:sin-3(tm1276)_downregulated |
| | | cgc4489_group_4 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00034739:N2moreDR1350 |
| | | WBPaper00040858:eQTL_age_regulated_aging |
| | | WBPaper00040858:eQTL_regulated_aging |
| | | WBPaper00040985:AIN-2_asynchronous_intestine |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00048989:N2_allantoin_upregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_SM |
| | | [cgc6390]:herm_sex-enriched |
| | Interaction (72) |
| | Anatomy_function | WBbtf0086 |
| | | WBbtf1049 |
| Map_info | Map | III | Position | -0.951383 | Error | 0.006326 |
| | Well_ordered |
| | Positive | Positive_clone | C28A6 |
| | | | Y102E9 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Negative | Negative_clone | F37A4 | Author_evidence | Dwyer ND |
| | | | K07E12 | Author_evidence | Dwyer ND |
| | Mapping_data | Multi_point | 2055 |
| | | | 2056 |
| | | | 2057 |
| | | | 2058 |
| | | | 4976 |
| | | | 5453 |
| | | Pos_neg_data | 5983 |
| Reference (40) |
| Remark | Data extracted from Dwyer et al. (1998) |
| Method | Gene |