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WormBase Tree Display for Gene: WBGene00003851

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Name Class

WBGene00003851SMapS_parentSequenceY102E9
IdentityVersion1
NameCGC_nameodr-4Person_evidenceWBPerson42
Sequence_nameY102E9.1
Molecular_name (12)
Other_nameCELE_Y102E9.1Accession_evidenceNDBBX284603
Public_nameodr-4
DB_infoDatabaseAceViewgene3H823
WormQTLgeneWBGene00003851
WormFluxgeneWBGene00003851
NDBlocus_tagCELE_Y102E9.1
PanthergeneCAEEL|WormBase=WBGene00003851|UniProtKB=Q8I7F8
familyPTHR33966
NCBIgene175950
RefSeqproteinNM_001027644.9
NM_001382900.2
NM_001392129.1
SwissProtUniProtAccQ8I7F8
TREEFAMTREEFAM_IDTF320359
UniProt_GCRPUniProtAccQ8I7F8
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classodr
Allele (48)
Legacy_information[Bargmann CI] defective chemotaxis to volatile odorants
[C.elegansII] n2144 : defective chemotaxis to some volatile odoratants. n2144/Df similar. NA1. [Bargmann et al. 1993]
[Dwyer ND] n2144 defective in odorant response to benzaldehyde, diacetyl, normal response to isoamyl alcohol, pyrazine. Fails to localize ODR-10 to cilia of AWA neurons. n2144 rescued by subclone including Y102E9.1, encoding 445 aa protein. n2144 is M372L plus splice acceptor change.
StrainWBStrain00027204
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (31)
Structured_descriptionConcise_descriptionodr-4 encodes a novel type II membrane protein; ODR-4 is required for localization of a subset of G protein-coupled receptors (GPCRs)s, including ODR-10, to the cilia of olfactory neurons; ODR-4 affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; ODR-4 physically interacts with ODR-8 to form a complex at the endoplasmic reticulum membrane, and physically interacts wtih ODR-10, as well; ODR-4 is expressed in twelve pairs of chemosensory neurons: the ten amphid neurons and two phasmid neurons; odr-4 expression overlaps that of odr-8.Paper_evidenceWBPaper00003063
WBPaper00005511
WBPaper00044965
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated02 May 2014 00:00:00
Automated_descriptionInvolved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY102E9.1a
Y102E9.1b
Y102E9.1c
Corresponding_transcriptY102E9.1a.1
Y102E9.1a.2
Y102E9.1a.3
Y102E9.1a.4
Y102E9.1b.1
Y102E9.1c.1
Other_sequence (31)
Associated_featureWBsf042313
WBsf645280
WBsf645281
WBsf992840
WBsf1015145
WBsf225148
Experimental_infoRNAi_resultWBRNAi00005178Inferred_automaticallyRNAi_primary
WBRNAi00055160Inferred_automaticallyRNAi_primary
WBRNAi00005789Inferred_automaticallyRNAi_primary
WBRNAi00055159Inferred_automaticallyRNAi_primary
WBRNAi00005790Inferred_automaticallyRNAi_primary
WBRNAi00055161Inferred_automaticallyRNAi_primary
WBRNAi00055157Inferred_automaticallyRNAi_primary
WBRNAi00019822Inferred_automaticallyRNAi_primary
WBRNAi00005720Inferred_automaticallyRNAi_primary
WBRNAi00027800Inferred_automaticallyRNAi_primary
Expr_patternExpr1432
Expr10139
Expr11650
Expr13173
Expr1011843
Expr1031817
Expr1158687
Expr2014610
Expr2032843
Drives_constructWBCnstr00010274
WBCnstr00019303
WBCnstr00021696
WBCnstr00035829
WBCnstr00041883
Construct_productWBCnstr00010274
WBCnstr00019303
WBCnstr00035829
Microarray_results (36)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032031:DConiospora_downregulated_OligoArray_24h
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038289:oocyte_protein
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045774:clk-1_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:cytoplasm_specific
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053388:dauer_regulated_Cluster3
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058942:henn-1(pk2295)_downregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059471:EGL-43_interacting
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061340:ADF
WBPaper00061340:ADF_AWB
WBPaper00061340:ADL
WBPaper00061340:ASG
WBPaper00061340:ASG_AWA
WBPaper00061340:ASH
WBPaper00061340:ASI
WBPaper00061340:ASJ
WBPaper00061340:ASK
WBPaper00061340:AWA
WBPaper00061340:AWB
WBPaper00061340:AWC
WBPaper00061527:C30H6.7-Y106G6H.5_2231
WBPaper00061651:ADF_enriched
WBPaper00061651:ADL_enriched
WBPaper00061651:ASH_enriched
WBPaper00061651:ASI_enriched
WBPaper00061651:ASJ_enriched
WBPaper00061651:ASK_enriched
WBPaper00061651:AWB_enriched
WBPaper00061651:PHA_enriched
WBPaper00061651:PHB_enriched
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064494:postdauer_downregulated_AWA
WBPaper00064716:paraquat_upregulated
WBPaper00064789:Day6_vs_Day1_upregulated_neuron
WBPaper00064789:Day9_vs_Day1_upregulated_neuron
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066085:hda-3(ok1991)_downregulated
WBPaper00066085:sin-3(tm1276)_downregulated
cgc4489_group_4
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00034739:N2moreDR1350
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_regulated_aging
WBPaper00040985:AIN-2_asynchronous_intestine
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:herm_sex-enriched
Interaction (72)
Anatomy_functionWBbtf0086
WBbtf1049
Map_infoMapIIIPosition-0.951383Error0.006326
Well_ordered
PositivePositive_cloneC28A6
Y102E9Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeNegative_cloneF37A4Author_evidenceDwyer ND
K07E12Author_evidenceDwyer ND
Mapping_dataMulti_point2055
2056
2057
2058
4976
5453
Pos_neg_data5983
Reference (40)
RemarkData extracted from Dwyer et al. (1998)
MethodGene