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WormBase Tree Display for Gene: WBGene00003851

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Name Class

WBGene00003851SMapS_parentSequenceY102E9
IdentityVersion1
NameCGC_nameodr-4Person_evidenceWBPerson42
Sequence_nameY102E9.1
Molecular_name (12)
Other_nameCELE_Y102E9.1Accession_evidenceNDBBX284603
Public_nameodr-4
DB_infoDatabaseAceViewgene3H823
WormQTLgeneWBGene00003851
WormFluxgeneWBGene00003851
NDBlocus_tagCELE_Y102E9.1
PanthergeneCAEEL|WormBase=WBGene00003851|UniProtKB=Q8I7F8
familyPTHR33966
NCBIgene175950
RefSeqproteinNM_001027644.9
NM_001382900.2
NM_001392129.1
SwissProtUniProtAccQ8I7F8
TREEFAMTREEFAM_IDTF320359
UniProt_GCRPUniProtAccQ8I7F8
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classodr
Allele (48)
Legacy_information[Bargmann CI] defective chemotaxis to volatile odorants
[C.elegansII] n2144 : defective chemotaxis to some volatile odoratants. n2144/Df similar. NA1. [Bargmann et al. 1993]
[Dwyer ND] n2144 defective in odorant response to benzaldehyde, diacetyl, normal response to isoamyl alcohol, pyrazine. Fails to localize ODR-10 to cilia of AWA neurons. n2144 rescued by subclone including Y102E9.1, encoding 445 aa protein. n2144 is M372L plus splice acceptor change.
StrainWBStrain00027204
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (31)
Structured_descriptionConcise_descriptionodr-4 encodes a novel type II membrane protein; ODR-4 is required for localization of a subset of G protein-coupled receptors (GPCRs)s, including ODR-10, to the cilia of olfactory neurons; ODR-4 affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; ODR-4 physically interacts with ODR-8 to form a complex at the endoplasmic reticulum membrane, and physically interacts wtih ODR-10, as well; ODR-4 is expressed in twelve pairs of chemosensory neurons: the ten amphid neurons and two phasmid neurons; odr-4 expression overlaps that of odr-8.Paper_evidenceWBPaper00003063
WBPaper00005511
WBPaper00044965
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated02 May 2014 00:00:00
Automated_descriptionInvolved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY102E9.1a
Y102E9.1b
Y102E9.1c
Corresponding_transcriptY102E9.1a.1
Y102E9.1a.2
Y102E9.1a.3
Y102E9.1a.4
Y102E9.1b.1
Y102E9.1c.1
Other_sequence (31)
Associated_featureWBsf042313
WBsf645280
WBsf645281
WBsf992840
WBsf1015145
WBsf225148
Experimental_infoRNAi_resultWBRNAi00005178Inferred_automaticallyRNAi_primary
WBRNAi00055160Inferred_automaticallyRNAi_primary
WBRNAi00005789Inferred_automaticallyRNAi_primary
WBRNAi00055159Inferred_automaticallyRNAi_primary
WBRNAi00005790Inferred_automaticallyRNAi_primary
WBRNAi00055161Inferred_automaticallyRNAi_primary
WBRNAi00055157Inferred_automaticallyRNAi_primary
WBRNAi00019822Inferred_automaticallyRNAi_primary
WBRNAi00005720Inferred_automaticallyRNAi_primary
WBRNAi00027800Inferred_automaticallyRNAi_primary
Expr_patternExpr1432
Expr10139
Expr11650
Expr13173
Expr1011843
Expr1031817
Expr1158687
Expr2014610
Expr2032843
Drives_constructWBCnstr00010274
WBCnstr00019303
WBCnstr00021696
WBCnstr00035829
WBCnstr00041883
Construct_productWBCnstr00010274
WBCnstr00019303
WBCnstr00035829
Microarray_results (36)
Expression_cluster (103)
InteractionWBInteraction000000624
WBInteraction000001834
WBInteraction000001837
WBInteraction000003175
WBInteraction000028396
WBInteraction000028452
WBInteraction000031454
WBInteraction000031455
WBInteraction000147210
WBInteraction000150158
WBInteraction000163618
WBInteraction000165168
WBInteraction000166141
WBInteraction000166148
WBInteraction000180108
WBInteraction000180431
WBInteraction000195996
WBInteraction000199363
WBInteraction000208087
WBInteraction000208417
WBInteraction000229513
WBInteraction000231654
WBInteraction000233992
WBInteraction000249922
WBInteraction000251054
WBInteraction000264026
WBInteraction000277614
WBInteraction000278050
WBInteraction000279431
WBInteraction000287037
WBInteraction000289127
WBInteraction000292151
WBInteraction000293033
WBInteraction000293887
WBInteraction000296151
WBInteraction000297400
WBInteraction000297838
WBInteraction000301092
WBInteraction000301836
WBInteraction000316775
WBInteraction000324554
WBInteraction000325341
WBInteraction000326338
WBInteraction000342730
WBInteraction000350301
WBInteraction000351174
WBInteraction000354440
WBInteraction000359817
WBInteraction000365259
WBInteraction000369372
WBInteraction000373428
WBInteraction000376569
WBInteraction000376667
WBInteraction000383867
WBInteraction000386772
WBInteraction000387620
WBInteraction000405520
WBInteraction000410598
WBInteraction000410895
WBInteraction000416223
WBInteraction000417561
WBInteraction000417631
WBInteraction000434147
WBInteraction000437910
WBInteraction000442151
WBInteraction000442660
WBInteraction000446253
WBInteraction000447827
WBInteraction000447965
WBInteraction000501699
WBInteraction000555262
WBInteraction000555263
Anatomy_functionWBbtf0086
WBbtf1049
Map_infoMapIIIPosition-0.951383Error0.006326
Well_ordered
PositivePositive_cloneC28A6
Y102E9Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeNegative_cloneF37A4Author_evidenceDwyer ND
K07E12Author_evidenceDwyer ND
Mapping_dataMulti_point2055
2056
2057
2058
4976
5453
Pos_neg_data5983
Reference (40)
RemarkData extracted from Dwyer et al. (1998)
MethodGene