WormBase Tree Display for Gene: WBGene00003017
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| WBGene00003017 | SMap | S_parent | Sequence | K10G6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lin-31 | Person_evidence | WBPerson261 | |||||
| Sequence_name | K10G6.1 | ||||||||
| Molecular_name | K10G6.1 | ||||||||
| K10G6.1.1 | |||||||||
| CE12098 | |||||||||
| Other_name | K10G6.a | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_K10G6.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | lin-31 | ||||||||
| DB_info | Database | AceView | gene | 2E275 | |||||
| WormQTL | gene | WBGene00003017 | |||||||
| WormFlux | gene | WBGene00003017 | |||||||
| NDB | locus_tag | CELE_K10G6.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003017|UniProtKB=P34683 | |||||||
| family | PTHR11829 | ||||||||
| NCBI | gene | 173740 | |||||||
| RefSeq | protein | NM_062303.5 | |||||||
| SwissProt | UniProtAcc | P34683 | |||||||
| UniProt_GCRP | UniProtAcc | P34683 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Reference_allele | WBVar00089401 | ||||||||
| Allele (127) | |||||||||
| Legacy_information | n301 : adult hermaphrodite Muv vulva either functional or nonfunctional protrusion 0-4 small ventral protrusions. ES3. Male gross morphology wildtype ME0. Similar phenotype in n301/Df. NA11 (e1750 n376 etc.). | ||||||||
| See also e1750, e2181, n301, n376, n428, n429, n435, n1048, n1049, n1050, n1053, n1282, n1289, n1290, n1291, n1292, n1293, n1294, n1300, n1301 | |||||||||
| [C.elegansII] n301 : adult hermaphrodite Muv, vulva either functional or nonfunctional protrusion; 0-4 small ventral protrusions. VPC cells adopt 1ary/2ary/3ary fate at random.ES3 (adult). Male gross morphology wildtype ME0. Similar phenotype in n301/Df. Mosaic analysis indicates cell-autonomous action.OA>10: e1750, e2181, n376, n428, n1301 etc. Cloned: 1.5 transcript, expressed throughout development, encodes predicted 237 aa protein with similarity to fork head/HNF-3 transcription factors. lin-31:GFP expressed in P3.p - P8.p. [Miller et al. 1993; SD] | |||||||||
| Strain (19) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00001434 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001438 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001440 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001441 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001442 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00002601 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00004013 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00006853 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003976 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000912 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | lin-31 encodes a winged helix (WH)-like transcription factor that is a member of the HNF3/Forkhead family of DNA-binding proteins; LIN-31 acts as a tissue-specific effector of MAP kinase-mediated signaling in the vulva; when MAP kinase is inactive, LIN-31 forms a complex with LIN-1/Ets that inhibits vulval cell fates; upon MAP kinase activation (vulval induction), LIN-31 becomes phosphorylated, dissociates from LIN-1, and goes on to promote primary and secondary vulval cell fates; LIN-31 is expressed in the vulval precursor cells. | Paper_evidence | WBPaper00003087 | |||||
| WBPaper00005344 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables sequence-specific DNA binding activity. Involved in vulval development. Located in nucleus. Expressed in several structures, including P11.p; P9.p; gonad; nerve ring; and vulval precursor cell. Is an ortholog of human FOXB2 (forkhead box B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K10G6.1 | |||||||
| Corresponding_transcript | K10G6.1.1 | ||||||||
| Other_sequence | GR12061 | ||||||||
| FC540606.1 | |||||||||
| XIC04591_1 | |||||||||
| Acan_isotig11162 | |||||||||
| Oden_isotig20815 | |||||||||
| Hbac_isotig03213 | |||||||||
| ACC18989_1 | |||||||||
| Dviv_isotig22537 | |||||||||
| GRC00772_1 | |||||||||
| Associated_feature (13) | |||||||||
| Transcription_factor | WBTranscriptionFactor000183 | ||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr1086 | ||||||||
| Expr1430 | |||||||||
| Expr1513 | |||||||||
| Expr6382 | |||||||||
| Expr7614 | |||||||||
| Expr10798 | |||||||||
| Expr1018210 | |||||||||
| Expr1154262 | |||||||||
| Expr2013174 | |||||||||
| Expr2031406 | |||||||||
| Drives_construct (27) | |||||||||
| Construct_product | WBCnstr00000529 | ||||||||
| Antibody | WBAntibody00000176 | ||||||||
| WBAntibody00000914 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (54) | |||||||||
| WBProcess | WBbiopr:00000025 | ||||||||
| Map_info | Map | II | Position | -5.87555 | Error | 0.040806 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | nDf2 | |||||||
| nDf3 | |||||||||
| nDf4 | |||||||||
| mDf14 | |||||||||
| mDf15 | |||||||||
| mDf16 | |||||||||
| Positive_clone | K10G6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Negative | Outside_rearr | mDf13 | |||||||
| Mapping_data | 2_point | 783 | |||||||
| 784 | |||||||||
| Multi_point (21) | |||||||||
| Pos_neg_data (18) | |||||||||
| Landmark_gene | |||||||||
| Reference (181) | |||||||||
| Method | Gene |
