WormBase Tree Display for Gene: WBGene00002348

WBGene00002348 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 2
    Name: CGC_name: myo-1 Person_evidence: WBPerson261
      Sequence_name: R06C7.10
      Molecular_name: R06C7.10
        R06C7.10.1
        CE06253
      Other_name: myosin I Accession_evidence: EMBL M37234
        CELE_R06C7.10 Accession_evidence: NDB BX284601
      Public_name: myo-1
    DB_info: Database: AceView gene 1H836
        WormQTL gene WBGene00002348
        WormFlux gene WBGene00002348
        NDB locus_tag CELE_R06C7.10
        Panther gene CAEEL|WormBase=WBGene00002348|UniProtKB=P02567
          family PTHR45615
        NCBI gene 172471
        RefSeq protein NM_059652.7
        SwissProt UniProtAcc P02567
        UniProt_GCRP UniProtAcc P02567
        OMIM gene 160720
            160740
            160741
            160760
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 20 Oct 2010 10:47:45 WBPerson2970 Event: Split_into: WBGene00202503
      Split_into: WBGene00202503
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: myo
    Allele (90)
    Strain: WBStrain00051410
    RNASeq_FPKM (74)
    GO_annotation (23)
    Ortholog (83)
    Paralog: WBGene00006789 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003515 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009730 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00019064 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012437 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003514 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003776 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003777 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002035 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002036 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002037 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002038 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002039 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002040 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00002041 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004969 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006754 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015356 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015968 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018317 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018377 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: A structural constituent of muscle. Involved in muscle contraction and pharyngeal pumping. Located in striated muscle myosin thick filament. Expressed in pharynx. Human ortholog(s) of this gene implicated in several diseases, including contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A; distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (23)
  Molecular_info: Corresponding_CDS: R06C7.10
    Corresponding_transcript: R06C7.10.1
    Other_sequence (55)
    Associated_feature (15)
  Experimental_info: RNAi_result: WBRNAi00051383 Inferred_automatically: RNAi_primary
      WBRNAi00060113 Inferred_automatically: RNAi_primary
      WBRNAi00026040 Inferred_automatically: RNAi_primary
      WBRNAi00066667 Inferred_automatically: RNAi_primary
      WBRNAi00060111 Inferred_automatically: RNAi_primary
      WBRNAi00060112 Inferred_automatically: RNAi_primary
      WBRNAi00060110 Inferred_automatically: RNAi_primary
      WBRNAi00022415 Inferred_automatically: RNAi_primary
      WBRNAi00066718 Inferred_automatically: RNAi_primary
      WBRNAi00026041 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2731
      Expr1014691
      Expr1031351
      Expr1155073
      Expr2013841
      Expr2032081
    Antibody: WBAntibody00000012
    Microarray_results (19)
    Expression_cluster (259)
    Interaction (143)
  Map_info: Positive: Positive_clone: R06C7 Inferred_automatically: From sequence, transcript, pseudogene data
        SG25/26
    Mapping_data: 2_point: 5116
        5117
      Multi_point: 279
        814
        1784
        4477
        5056
      Pos_neg_data (12)
    Interpolated_map_position: I 1.86572
  Reference (61)
  Remark: yk10b9.3 removed from sequence list. sdm 11/00
    let-75 was previously renamed to myo-1, but has been reverted back to let-75 due to historical precedence [021117 ck1]
  Method: Gene